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Page 1
NVC-422 inactivates Staphylococcus aureus toxins.
Jekle A, Yoon J, Zuck M, Najafi R, Wang L, Shiau T, Francavilla C, Rani SA, Eitzinger C, Nagl M, Anderson M, Debabov D. Jekle A, et al. Among authors: francavilla c. Antimicrob Agents Chemother. 2013 Feb;57(2):924-9. doi: 10.1128/AAC.01945-12. Epub 2012 Dec 3. Antimicrob Agents Chemother. 2013. PMID: 23208720 Free PMC article.
Novel N-chloroheterocyclic antimicrobials.
Francavilla C, Turtle ED, Kim B, O'Mahony DJ, Shiau TP, Low E, Alvarez NJ, Celeri CE, D'Lima L, Friedman LC, Ruado FS, Xu P, Zuck ME, Anderson MB, Najafi RR, Jain RK. Francavilla C, et al. Bioorg Med Chem Lett. 2011 May 15;21(10):3029-33. doi: 10.1016/j.bmcl.2011.03.035. Epub 2011 Mar 16. Bioorg Med Chem Lett. 2011. PMID: 21459574
Novel 3-chlorooxazolidin-2-ones as antimicrobial agents.
Shiau TP, Turtle ED, Francavilla C, Alvarez NJ, Zuck M, Friedman L, O'Mahony DJ, Low E, Anderson MB, Najafi RR, Jain RK. Shiau TP, et al. Among authors: francavilla c. Bioorg Med Chem Lett. 2011 May 15;21(10):3025-8. doi: 10.1016/j.bmcl.2011.03.036. Epub 2011 Mar 21. Bioorg Med Chem Lett. 2011. PMID: 21470861
Structure stability/activity relationships of sulfone stabilized N,N-dichloroamines.
Low E, Kim B, Francavilla C, Shiau TP, Turtle ED, O'Mahony DJ, Alvarez N, Houchin A, Xu P, Zuck M, Celeri C, Anderson MB, Najafi RR, Jain RK. Low E, et al. Among authors: francavilla c. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3682-5. doi: 10.1016/j.bmcl.2011.04.084. Epub 2011 Apr 24. Bioorg Med Chem Lett. 2011. PMID: 21570284
Sulfonyl-polyol N,N-dichloroamines with rapid, broad-spectrum antimicrobial activity.
Shiau TP, Low E, Kim B, Turtle ED, Francavilla C, O'Mahony DJ, Friedman L, D'Lima L, Jekle A, Debabov D, Zuck M, Alvarez NJ, Anderson M, Najafi RR, Jain RK. Shiau TP, et al. Among authors: francavilla c. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5650-3. doi: 10.1016/j.bmcl.2013.08.027. Epub 2013 Aug 17. Bioorg Med Chem Lett. 2013. PMID: 23999044
Quaternary ammonium N,N-dichloroamines as topical, antimicrobial agents.
Francavilla C, Low E, Nair S, Kim B, Shiau TP, Debabov D, Celeri C, Alvarez N, Houchin A, Xu P, Najafi R, Jain R. Francavilla C, et al. Bioorg Med Chem Lett. 2009 May 15;19(10):2731-4. doi: 10.1016/j.bmcl.2009.03.120. Epub 2009 Mar 28. Bioorg Med Chem Lett. 2009. PMID: 19362467
Formal synthesis of (+)-discodermolide.
Francavilla C, Chen W, Kinder FR Jr. Francavilla C, et al. Org Lett. 2003 Apr 17;5(8):1233-6. doi: 10.1021/ol034186t. Org Lett. 2003. PMID: 12688727
Engineering of pH-dependent antigen binding properties for toxin-targeting IgG1 antibodies using light-chain shuffling.
Tulika T, Ruso-Julve F, Ahmadi S, Ljungars A, Rivera-de-Torre E, Wade J, Fernández-Quintero ML, Jenkins TP, Belfakir SB, Ross GMS, Boyens-Thiele L, Buell AK, Sakya SA, Sørensen CV, Bohn MF, Ledsgaard L, Voldborg BG, Francavilla C, Schlothauer T, Lomonte B, Andersen JT, Laustsen AH. Tulika T, et al. Among authors: francavilla c. Structure. 2024 Sep 5;32(9):1404-1418.e7. doi: 10.1016/j.str.2024.07.014. Epub 2024 Aug 14. Structure. 2024. PMID: 39146931 Free PMC article.
61 results