Brady NR - Search Results

1

Modulation of serines 17 and 24 in the LC3-interacting region of Bnip3 determines pro-survival mitophagy versus apoptosis.

Zhu Y, Massen S, Terenzio M, Lang V, Chen-Lindner S, Eils R, Novak I, Dikic I, Hamacher-Brady A, Brady NR. Zhu Y, et al. Among authors: brady nr. J Biol Chem. 2013 Jan 11;288(2):1099-113. doi: 10.1074/jbc.M112.399345. Epub 2012 Dec 3. J Biol Chem. 2013. PMID: 23209295 Free PMC article.

2

Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.

Hamacher-Brady A, Brady NR. Hamacher-Brady A, et al. Among authors: brady nr. J Biol Chem. 2015 Sep 4;290(36):22005-18. doi: 10.1074/jbc.M115.643064. Epub 2015 Jul 1. J Biol Chem. 2015. PMID: 26134559 Free PMC article.

3

Autophagy capacity and sub-mitochondrial heterogeneity shape Bnip3-induced mitophagy regulation of apoptosis.

Choe SC, Hamacher-Brady A, Brady NR. Choe SC, et al. Among authors: brady nr. Cell Commun Signal. 2015 Aug 8;13:37. doi: 10.1186/s12964-015-0115-9. Cell Commun Signal. 2015. PMID: 26253153 Free PMC article.

4

Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy.

Hamacher-Brady A, Brady NR. Hamacher-Brady A, et al. Among authors: brady nr. Cell Mol Life Sci. 2016 Feb;73(4):775-95. doi: 10.1007/s00018-015-2087-8. Epub 2015 Nov 26. Cell Mol Life Sci. 2016. PMID: 26611876 Free PMC article. Review.

5

Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production.

Hamacher-Brady A, Stein HA, Turschner S, Toegel I, Mora R, Jennewein N, Efferth T, Eils R, Brady NR. Hamacher-Brady A, et al. Among authors: brady nr. J Biol Chem. 2011 Feb 25;286(8):6587-601. doi: 10.1074/jbc.M110.210047. Epub 2010 Dec 13. J Biol Chem. 2011. PMID: 21149439 Free PMC article.

6

Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins.

Rogov VV, Suzuki H, Marinković M, Lang V, Kato R, Kawasaki M, Buljubašić M, Šprung M, Rogova N, Wakatsuki S, Hamacher-Brady A, Dötsch V, Dikic I, Brady NR, Novak I. Rogov VV, et al. Among authors: brady nr. Sci Rep. 2017 Apr 25;7(1):1131. doi: 10.1038/s41598-017-01258-6. Sci Rep. 2017. PMID: 28442745 Free PMC article.

7

Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.

Hamacher-Brady A, Choe SC, Krijnse-Locker J, Brady NR. Hamacher-Brady A, et al. Among authors: brady nr. Cell Death Differ. 2014 Dec;21(12):1862-76. doi: 10.1038/cdd.2014.101. Epub 2014 Aug 1. Cell Death Differ. 2014. PMID: 25080938 Free PMC article.

8

Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy.

Hundeshagen P, Hamacher-Brady A, Eils R, Brady NR. Hundeshagen P, et al. Among authors: brady nr. BMC Biol. 2011 Jun 2;9:38. doi: 10.1186/1741-7007-9-38. BMC Biol. 2011. PMID: 21635740 Free PMC article.

9

Multi-parametric analysis and modeling of relationships between mitochondrial morphology and apoptosis.

Reis Y, Bernardo-Faura M, Richter D, Wolf T, Brors B, Hamacher-Brady A, Eils R, Brady NR. Reis Y, et al. Among authors: brady nr. PLoS One. 2012;7(1):e28694. doi: 10.1371/journal.pone.0028694. Epub 2012 Jan 17. PLoS One. 2012. PMID: 22272225 Free PMC article.

10

Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes.

Hamacher-Brady A, Brady NR, Gottlieb RA. Hamacher-Brady A, et al. Among authors: brady nr. J Biol Chem. 2006 Oct 6;281(40):29776-87. doi: 10.1074/jbc.M603783200. Epub 2006 Aug 1. J Biol Chem. 2006. PMID: 16882669 Free article.

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