Liu Y - Search Results

1

An organic molecule modulated chemoselective cyclization of alkynyl nitriles tethered to 2-alkyl substituted chromones with multireactive sites.

Huang L, Liu Y, Xie F, Hu Y. Huang L, et al. Among authors: liu y. Org Lett. 2012 Dec 21;14(24):6122-5. doi: 10.1021/ol302964x. Epub 2012 Dec 4. Org Lett. 2012. PMID: 23210678

2

Microwave assisted tandem Heck-Sonogashira reactions of N,N-di-Boc-protected 6-amino-5-iodo-2-methyl pyrimidin-4-ol in an efficient approach to functionalized pyrido[2,3-d]pyrimidines.

Liu Y, Jin S, Wang Z, Song L, Hu Y. Liu Y, et al. Org Lett. 2014 Jul 3;16(13):3524-7. doi: 10.1021/ol501459e. Epub 2014 Jun 23. Org Lett. 2014. PMID: 24956126

3

Phase transfer reagent promoted tandem ring-opening and ring-closing reactions of unique 3-(1-alkynyl) chromones.

Liu Y, Jin S, Huang L, Hu Y. Liu Y, et al. Org Lett. 2015 May 1;17(9):2134-7. doi: 10.1021/acs.orglett.5b00721. Epub 2015 Apr 22. Org Lett. 2015. PMID: 25901646

4

Base-promoted one-pot tandem reaction of 3-(1-alkynyl)chromones under microwave irradiation to functionalized amino-substituted xanthones.

Liu Y, Huang L, Xie F, Hu Y. Liu Y, et al. J Org Chem. 2010 Sep 17;75(18):6304-7. doi: 10.1021/jo1013614. J Org Chem. 2010. PMID: 20738144

5

Synthesis of novel functional polycyclic chromones through Michael addition and double cyclizations.

Liu Y, Huang L, Xie F, Chen X, Hu Y. Liu Y, et al. Org Biomol Chem. 2011 Apr 21;9(8):2680-4. doi: 10.1039/c0ob01000f. Epub 2011 Mar 2. Org Biomol Chem. 2011. PMID: 21369579

6

Identification and synthesis of substituted pyrrolo[2,3-d]pyrimidines as novel firefly luciferase inhibitors.

Liu Y, Fang J, Cai H, Xiao F, Ding K, Hu Y. Liu Y, et al. Bioorg Med Chem. 2012 Sep 15;20(18):5473-82. doi: 10.1016/j.bmc.2012.07.035. Epub 2012 Jul 28. Bioorg Med Chem. 2012. PMID: 22898255

7

Design and synthesis of novel benzo[d]oxazol-2(3H)-one derivatives bearing 7-substituted-4-enthoxyquinoline moieties as c-Met kinase inhibitors.

Lu D, Shen A, Liu Y, Peng X, Xing W, Ai J, Geng M, Hu Y. Lu D, et al. Among authors: liu y. Eur J Med Chem. 2016 Jun 10;115:191-200. doi: 10.1016/j.ejmech.2016.03.027. Epub 2016 Mar 12. Eur J Med Chem. 2016. PMID: 27017548

8

Enhancing the cellular anti-proliferation activity of pyridazinones as c-met inhibitors using docking analysis.

Xing W, Ai J, Jin S, Shi Z, Peng X, Wang L, Ji Y, Lu D, Liu Y, Geng M, Hu Y. Xing W, et al. Among authors: liu y. Eur J Med Chem. 2015 May 5;95:302-12. doi: 10.1016/j.ejmech.2015.03.041. Epub 2015 Mar 21. Eur J Med Chem. 2015. PMID: 25827399

9

Pyridazinone derivatives displaying highly potent and selective inhibitory activities against c-Met tyrosine kinase.

Liu Y, Jin S, Peng X, Lu D, Zeng L, Sun Y, Ai J, Geng M, Hu Y. Liu Y, et al. Eur J Med Chem. 2016 Jan 27;108:322-333. doi: 10.1016/j.ejmech.2015.11.042. Epub 2015 Nov 30. Eur J Med Chem. 2016. PMID: 26698536

10

Y-632 inhibits heat shock protein 90 (Hsp90) function by disrupting the interaction between Hsp90 and Hsp70/Hsp90 organizing protein, and exerts antitumor activity in vitro and in vivo.

Wang W, Liu Y, Zhao Z, Xie C, Xu Y, Hu Y, Quan H, Lou L. Wang W, et al. Among authors: liu y. Cancer Sci. 2016 Jun;107(6):782-90. doi: 10.1111/cas.12934. Epub 2016 Apr 27. Cancer Sci. 2016. PMID: 27002306 Free PMC article.

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