Gruber TD - Search Results

1

Structure-activity relationships of antitubercular salicylanilides consistent with disruption of the proton gradient via proton shuttling.

Lee IY, Gruber TD, Samuels A, Yun M, Nam B, Kang M, Crowley K, Winterroth B, Boshoff HI, Barry CE 3rd. Lee IY, et al. Among authors: gruber td. Bioorg Med Chem. 2013 Jan 1;21(1):114-26. doi: 10.1016/j.bmc.2012.10.056. Epub 2012 Nov 15. Bioorg Med Chem. 2013. PMID: 23211970 Free PMC article.

2

Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosis.

Chakraborty S, Gruber T, Barry CE 3rd, Boshoff HI, Rhee KY. Chakraborty S, et al. Science. 2013 Jan 4;339(6115):88-91. doi: 10.1126/science.1228980. Epub 2012 Nov 1. Science. 2013. PMID: 23118010 Free PMC article.

3

The highly crystalline PET found in plastic water bottles does not support the growth of the PETase-producing bacterium Ideonella sakaiensis.

Wallace NE, Adams MC, Chafin AC, Jones DD, Tsui CL, Gruber TD. Wallace NE, et al. Among authors: gruber td. Environ Microbiol Rep. 2020 Oct;12(5):578-582. doi: 10.1111/1758-2229.12878. Epub 2020 Sep 6. Environ Microbiol Rep. 2020. PMID: 32783383

4

DNA Electrophoresis Using Thiazole Orange Instead of Ethidium Bromide or Alternative Dyes.

O'Neil CS, Beach JL, Gruber TD. O'Neil CS, et al. Among authors: gruber td. J Vis Exp. 2019 Mar 31;(145). doi: 10.3791/59341. J Vis Exp. 2019. PMID: 30985761

5

Cell-Specific Chemical Delivery Using a Selective Nitroreductase-Nitroaryl Pair.

Gruber TD, Krishnamurthy C, Grimm JB, Tadross MR, Wysocki LM, Gartner ZJ, Lavis LD. Gruber TD, et al. ACS Chem Biol. 2018 Oct 19;13(10):2888-2896. doi: 10.1021/acschembio.8b00524. Epub 2018 Aug 29. ACS Chem Biol. 2018. PMID: 30111097 Free article.

6

Thiazole orange as an everyday replacement for ethidium bromide and costly DNA dyes for electrophoresis.

O'Neil CS, Beach JL, Gruber TD. O'Neil CS, et al. Among authors: gruber td. Electrophoresis. 2018 Jun;39(12):1474-1477. doi: 10.1002/elps.201700489. Epub 2018 May 4. Electrophoresis. 2018. PMID: 29645293

7

Semisynthetic fluorescent pH sensors for imaging exocytosis and endocytosis.

Martineau M, Somasundaram A, Grimm JB, Gruber TD, Choquet D, Taraska JW, Lavis LD, Perrais D. Martineau M, et al. Among authors: gruber td. Nat Commun. 2017 Nov 10;8(1):1412. doi: 10.1038/s41467-017-01752-5. Nat Commun. 2017. PMID: 29123102 Free PMC article.

8

Virginia Orange: A Versatile, Red-Shifted Fluorescein Scaffold for Single- and Dual-Input Fluorogenic Probes.

Grimm JB, Gruber TD, Ortiz G, Brown TA, Lavis LD. Grimm JB, et al. Among authors: gruber td. Bioconjug Chem. 2016 Feb 17;27(2):474-80. doi: 10.1021/acs.bioconjchem.5b00566. Epub 2015 Dec 22. Bioconjug Chem. 2016. PMID: 26636613 Free article.

9

X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin.

Gruber TD, Westler WM, Kiessling LL, Forest KT. Gruber TD, et al. Biochemistry. 2009 Oct 6;48(39):9171-3. doi: 10.1021/bi901437v. Biochemistry. 2009. PMID: 19719175 Free PMC article.

10

Ligand binding and substrate discrimination by UDP-galactopyranose mutase.

Gruber TD, Borrok MJ, Westler WM, Forest KT, Kiessling LL. Gruber TD, et al. J Mol Biol. 2009 Aug 14;391(2):327-40. doi: 10.1016/j.jmb.2009.05.081. Epub 2009 Jun 3. J Mol Biol. 2009. PMID: 19500588 Free PMC article.

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