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Incorporation of Phosphonate into Benzonaphthyridine Toll-like Receptor 7 Agonists for Adsorption to Aluminum Hydroxide.
Cortez A, Li Y, Miller AT, Zhang X, Yue K, Maginnis J, Hampton J, Hall de S, Shapiro M, Nayak B, D'Oro U, Li C, Skibinski D, Mbow ML, Singh M, O'Hagan DT, Cooke MP, Valiante NM, Wu TY. Cortez A, et al. Among authors: wu ty. J Med Chem. 2016 Jun 23;59(12):5868-78. doi: 10.1021/acs.jmedchem.6b00489. Epub 2016 Jun 13. J Med Chem. 2016. PMID: 27270029
Rational design of small molecules as vaccine adjuvants.
Wu TY, Singh M, Miller AT, De Gregorio E, Doro F, D'Oro U, Skibinski DA, Mbow ML, Bufali S, Herman AE, Cortez A, Li Y, Nayak BP, Tritto E, Filippi CM, Otten GR, Brito LA, Monaci E, Li C, Aprea S, Valentini S, Calabrό S, Laera D, Brunelli B, Caproni E, Malyala P, Panchal RG, Warren TK, Bavari S, O'Hagan DT, Cooke MP, Valiante NM. Wu TY, et al. Sci Transl Med. 2014 Nov 19;6(263):263ra160. doi: 10.1126/scitranslmed.3009980. Sci Transl Med. 2014. PMID: 25411473
A Dual Inhibitor of DYRK1A and GSK3β for β-Cell Proliferation: Aminopyrazine Derivative GNF4877.
Liu YA, Jin Q, Ding Q, Hao X, Mo T, Yan S, Zou Y, Huang Z, Zhang X, Gao W, Wu TY, Li C, Bursalaya B, Di Donato M, Zhang YQ, Deaton L, Shen W, Taylor B, Kamireddy A, Harb G, Li J, Jia Y, Schumacher AM, Laffitte B, Glynne R, Pan S, McNamara P, Molteni V, Loren J. Liu YA, et al. Among authors: wu ty. ChemMedChem. 2020 Aug 19;15(16):1562-1570. doi: 10.1002/cmdc.202000183. Epub 2020 Jul 2. ChemMedChem. 2020. PMID: 32613743
Chlorophyllides repress gain-of-function p53 mutated HNSCC cell proliferation via activation of p73 and repression of p53 aggregation in vitro and in vivo.
Cai BH, Wang YT, Chen CC, Yeh FY, Lin YR, Lin YC, Wu TY, Wu KY, Lien CF, Shih YC, Shaw JF. Cai BH, et al. Among authors: wu ty. Biochim Biophys Acta Mol Basis Dis. 2025 Jan 7;1871(3):167662. doi: 10.1016/j.bbadis.2025.167662. Online ahead of print. Biochim Biophys Acta Mol Basis Dis. 2025. PMID: 39788216
880 results