Gardner KH - Search Results

1

Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules.

Guo Y, Partch CL, Key J, Card PB, Pashkov V, Patel A, Bruick RK, Wurdak H, Gardner KH. Guo Y, et al. Among authors: gardner kh. ACS Chem Biol. 2013 Mar 15;8(3):626-35. doi: 10.1021/cb300604u. Epub 2012 Dec 26. ACS Chem Biol. 2013. PMID: 23240775 Free PMC article.

2

Structural basis for PAS domain heterodimerization in the basic helix--loop--helix-PAS transcription factor hypoxia-inducible factor.

Erbel PJ, Card PB, Karakuzu O, Bruick RK, Gardner KH. Erbel PJ, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15504-9. doi: 10.1073/pnas.2533374100. Epub 2003 Dec 10. Proc Natl Acad Sci U S A. 2003. PMID: 14668441 Free PMC article.

3

Identification and optimization of protein domains for NMR studies.

Card PB, Gardner KH. Card PB, et al. Among authors: gardner kh. Methods Enzymol. 2005;394:3-16. doi: 10.1016/S0076-6879(05)94001-9. Methods Enzymol. 2005. PMID: 15808215

4

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor.

Yang J, Zhang L, Erbel PJ, Gardner KH, Ding K, Garcia JA, Bruick RK. Yang J, et al. Among authors: gardner kh. J Biol Chem. 2005 Oct 28;280(43):36047-54. doi: 10.1074/jbc.M501755200. Epub 2005 Aug 29. J Biol Chem. 2005. PMID: 16129688 Free article.

5

Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.

Card PB, Erbel PJ, Gardner KH. Card PB, et al. Among authors: gardner kh. J Mol Biol. 2005 Oct 28;353(3):664-77. doi: 10.1016/j.jmb.2005.08.043. Epub 2005 Sep 6. J Mol Biol. 2005. PMID: 16181639

6

Hypoxia-inducible factors Per/ARNT/Sim domains: structure and function.

Scheuermann TH, Yang J, Zhang L, Gardner KH, Bruick RK. Scheuermann TH, et al. Among authors: gardner kh. Methods Enzymol. 2007;435:3-24. doi: 10.1016/S0076-6879(07)35001-5. Methods Enzymol. 2007. PMID: 17998046

7

Regulation of C-type lectin antimicrobial activity by a flexible N-terminal prosegment.

Mukherjee S, Partch CL, Lehotzky RE, Whitham CV, Chu H, Bevins CL, Gardner KH, Hooper LV. Mukherjee S, et al. Among authors: gardner kh. J Biol Chem. 2009 Feb 20;284(8):4881-8. doi: 10.1074/jbc.M808077200. Epub 2008 Dec 18. J Biol Chem. 2009. PMID: 19095652 Free PMC article.

8

Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.

Scheuermann TH, Tomchick DR, Machius M, Guo Y, Bruick RK, Gardner KH. Scheuermann TH, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):450-5. doi: 10.1073/pnas.0808092106. Epub 2009 Jan 7. Proc Natl Acad Sci U S A. 2009. PMID: 19129502 Free PMC article.

9

ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space.

Evans MR, Card PB, Gardner KH. Evans MR, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2617-22. doi: 10.1073/pnas.0808270106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196990 Free PMC article.

10

Molecular basis of coiled coil coactivator recruitment by the aryl hydrocarbon receptor nuclear translocator (ARNT).

Partch CL, Card PB, Amezcua CA, Gardner KH. Partch CL, et al. Among authors: gardner kh. J Biol Chem. 2009 May 29;284(22):15184-92. doi: 10.1074/jbc.M808479200. Epub 2009 Mar 26. J Biol Chem. 2009. PMID: 19324882 Free PMC article.

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