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Phase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor.
Kim KB, Kefford R, Pavlick AC, Infante JR, Ribas A, Sosman JA, Fecher LA, Millward M, McArthur GA, Hwu P, Gonzalez R, Ott PA, Long GV, Gardner OS, Ouellet D, Xu Y, DeMarini DJ, Le NT, Patel K, Lewis KD. Kim KB, et al. Among authors: xu y. J Clin Oncol. 2013 Feb 1;31(4):482-9. doi: 10.1200/JCO.2012.43.5966. Epub 2012 Dec 17. J Clin Oncol. 2013. PMID: 23248257 Free PMC article. Clinical Trial.
Safety, pharmacokinetic, pharmacodynamic, and efficacy data for the oral MEK inhibitor trametinib: a phase 1 dose-escalation trial.
Infante JR, Fecher LA, Falchook GS, Nallapareddy S, Gordon MS, Becerra C, DeMarini DJ, Cox DS, Xu Y, Morris SR, Peddareddigari VG, Le NT, Hart L, Bendell JC, Eckhardt G, Kurzrock R, Flaherty K, Burris HA 3rd, Messersmith WA. Infante JR, et al. Among authors: xu y. Lancet Oncol. 2012 Aug;13(8):773-81. doi: 10.1016/S1470-2045(12)70270-X. Epub 2012 Jul 16. Lancet Oncol. 2012. PMID: 22805291 Clinical Trial.
A comparison of the pharmacokinetics of the anticancer MET inhibitor foretinib free base tablet formulation to bisphosphate salt capsule formulation in patients with solid tumors.
Naing A, Kurzrock R, Adams LM, Kleha JF, Laubscher KH, Bonate PL, Weller S, Fitzgerald C, Xu Y, LoRusso PM. Naing A, et al. Among authors: xu y. Invest New Drugs. 2012 Feb;30(1):327-34. doi: 10.1007/s10637-010-9536-x. Epub 2010 Sep 15. Invest New Drugs. 2012. PMID: 20842406 Clinical Trial.
An evaluation of the drug interaction potential of pazopanib, an oral vascular endothelial growth factor receptor tyrosine kinase inhibitor, using a modified Cooperstown 5+1 cocktail in patients with advanced solid tumors.
Goh BC, Reddy NJ, Dandamudi UB, Laubscher KH, Peckham T, Hodge JP, Suttle AB, Arumugham T, Xu Y, Xu CF, Lager J, Dar MM, Lewis LD. Goh BC, et al. Among authors: xu cf, xu y. Clin Pharmacol Ther. 2010 Nov;88(5):652-9. doi: 10.1038/clpt.2010.158. Epub 2010 Sep 29. Clin Pharmacol Ther. 2010. PMID: 20881954 Clinical Trial.
Does cognitive intra-individual variability predict change in everyday functioning performance in women with and without HIV in the Women's Interagency HIV Study?
Vance DE, Xu Y, Dastgheyb R, Maki PM, Zhang J, Springer G, Anastos K, Gustafson DR, Weber KM, Dykxhoorn DM, Milam J, Diaz MM, Kassaye SG, Waldrop D, Lee J, Kempf MC, Konkle-Parker D, Goodkin K, Leviner AJ, Wright M, Jones D, Rubin LH. Vance DE, et al. Among authors: xu y. Appl Neuropsychol Adult. 2024 Dec 24:1-11. doi: 10.1080/23279095.2024.2444573. Online ahead of print. Appl Neuropsychol Adult. 2024. PMID: 39718250
Limitations in quantum metrology approaches to imaging resolution.
Iqbal S, Xu Y, Boyd RW. Iqbal S, et al. Among authors: xu y. Philos Trans A Math Phys Eng Sci. 2024 Dec 30;382(2287):20230332. doi: 10.1098/rsta.2023.0332. Epub 2024 Dec 24. Philos Trans A Math Phys Eng Sci. 2024. PMID: 39717977 Review.
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