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Antibacterial drug leads targeting isoprenoid biosynthesis.
Zhu W, Zhang Y, Sinko W, Hensler ME, Olson J, Molohon KJ, Lindert S, Cao R, Li K, Wang K, Wang Y, Liu YL, Sankovsky A, de Oliveira CA, Mitchell DA, Nizet V, McCammon JA, Oldfield E. Zhu W, et al. Among authors: olson j. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):123-8. doi: 10.1073/pnas.1219899110. Epub 2012 Dec 17. Proc Natl Acad Sci U S A. 2013. PMID: 23248302 Free PMC article.
Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens.
Lin L, Nonejuie P, Munguia J, Hollands A, Olson J, Dam Q, Kumaraswamy M, Rivera H Jr, Corriden R, Rohde M, Hensler ME, Burkart MD, Pogliano J, Sakoulas G, Nizet V. Lin L, et al. Among authors: olson j. EBioMedicine. 2015 Jun 10;2(7):690-8. doi: 10.1016/j.ebiom.2015.05.021. eCollection 2015 Jul. EBioMedicine. 2015. PMID: 26288841 Free PMC article.
TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin.
Swanson L, Katkar GD, Tam J, Pranadinata RF, Chareddy Y, Coates J, Anandachar MS, Castillo V, Olson J, Nizet V, Kufareva I, Das S, Ghosh P. Swanson L, et al. Among authors: olson j. Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26895-26906. doi: 10.1073/pnas.2011667117. Epub 2020 Oct 14. Proc Natl Acad Sci U S A. 2020. PMID: 33055214 Free PMC article.
A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection.
Okumura CY, Hollands A, Tran DN, Olson J, Dahesh S, von Köckritz-Blickwede M, Thienphrapa W, Corle C, Jeung SN, Kotsakis A, Shalwitz RA, Johnson RS, Nizet V. Okumura CY, et al. Among authors: olson j. J Mol Med (Berl). 2012 Sep;90(9):1079-89. doi: 10.1007/s00109-012-0882-3. Epub 2012 Feb 28. J Mol Med (Berl). 2012. PMID: 22371073 Free PMC article.
4,219 results