Gobec S - Search Results

1

Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure-activity relationships of nitroxoline derivatives.

Sosič I, Mirković B, Arenz K, Stefane B, Kos J, Gobec S. Sosič I, et al. Among authors: gobec s. J Med Chem. 2013 Jan 24;56(2):521-33. doi: 10.1021/jm301544x. Epub 2013 Jan 4. J Med Chem. 2013. PMID: 23252745

2

Phosphonate inhibitors of antigen 85C, a crucial enzyme involved in the biosynthesis of the Mycobacterium tuberculosis cell wall.

Gobec S, Plantan I, Mravljak J, Wilson RA, Besra GS, Kikelj D. Gobec S, et al. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3559-62. doi: 10.1016/j.bmcl.2004.04.052. Bioorg Med Chem Lett. 2004. PMID: 15177473

3

Recent advances in design, synthesis and biological activity of aminoalkylsulfonates and sulfonamidopeptides.

Obreza A, Gobec S. Obreza A, et al. Among authors: gobec s. Curr Med Chem. 2004 Dec;11(24):3263-78. doi: 10.2174/0929867043363659. Curr Med Chem. 2004. PMID: 15579012 Review.

4

Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.

Gobec S, Brozic P, Rizner TL. Gobec S, et al. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5170-5. doi: 10.1016/j.bmcl.2005.08.063. Epub 2005 Sep 23. Bioorg Med Chem Lett. 2005. PMID: 16183274

5

Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD.

Strancar K, Blanot D, Gobec S. Strancar K, et al. Among authors: gobec s. Bioorg Med Chem Lett. 2006 Jan 15;16(2):343-8. doi: 10.1016/j.bmcl.2005.09.086. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16271472

6

Flavonoids and cinnamic acid esters as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase: a synthesis, QSAR and modelling study.

Sova M, Perdih A, Kotnik M, Kristan K, Rizner TL, Solmajer T, Gobec S. Sova M, et al. Among authors: gobec s. Bioorg Med Chem. 2006 Nov 15;14(22):7404-18. doi: 10.1016/j.bmc.2006.07.027. Epub 2006 Aug 7. Bioorg Med Chem. 2006. PMID: 16891119

7

Inhibitors of cathepsin B.

Frlan R, Gobec S. Frlan R, et al. Among authors: gobec s. Curr Med Chem. 2006;13(19):2309-27. doi: 10.2174/092986706777935122. Curr Med Chem. 2006. PMID: 16918357 Review.

8

Design, synthesis, biochemical evaluation and antimycobacterial action of phosphonate inhibitors of antigen 85C, a crucial enzyme involved in biosynthesis of the mycobacterial cell wall.

Gobec S, Plantan I, Mravljak J, Svajger U, Wilson RA, Besra GS, Soares SL, Appelberg R, Kikelj D. Gobec S, et al. Eur J Med Chem. 2007 Jan;42(1):54-63. doi: 10.1016/j.ejmech.2006.08.007. Epub 2006 Sep 28. Eur J Med Chem. 2007. PMID: 17010479

9

New lipophilic phthalimido- and 3-phenoxybenzyl sulfonates: inhibition of antigen 85C mycolyltransferase activity and cytotoxicity.

Kovac A, Wilson RA, Besra GS, Filipic M, Kikelj D, Gobec S. Kovac A, et al. Among authors: gobec s. J Enzyme Inhib Med Chem. 2006 Aug;21(4):391-7. doi: 10.1080/14756360600703214. J Enzyme Inhib Med Chem. 2006. PMID: 17059171 Free article.

10

Diazenedicarboxamides as inhibitors of D-alanine-D-alanine ligase (Ddl).

Kovac A, Majce V, Lenarsic R, Bombek S, Bostock JM, Chopra I, Polanc S, Gobec S. Kovac A, et al. Among authors: gobec s. Bioorg Med Chem Lett. 2007 Apr 1;17(7):2047-54. doi: 10.1016/j.bmcl.2007.01.015. Epub 2007 Jan 17. Bioorg Med Chem Lett. 2007. PMID: 17267218

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