Grogan PT - Search Results

1

Antiproliferative withanolides from Datura wrightii.

Zhang H, Bazzill J, Gallagher RJ, Subramanian C, Grogan PT, Day VW, Kindscher K, Cohen MS, Timmermann BN. Zhang H, et al. Among authors: grogan pt. J Nat Prod. 2013 Mar 22;76(3):445-9. doi: 10.1021/np300766p. Epub 2012 Dec 19. J Nat Prod. 2013. PMID: 23252848 Free PMC article.

2

Withanolides from Physalis hispida.

Cao CM, Zhang H, Gallagher RJ, Day VW, Kindscher K, Grogan P, Cohen MS, Timmermann BN. Cao CM, et al. J Nat Prod. 2014 Mar 28;77(3):631-9. doi: 10.1021/np400953n. Epub 2014 Jan 23. J Nat Prod. 2014. PMID: 24456028

3

Novel natural withanolides induce apoptosis and inhibit migration of neuroblastoma cells through down regulation of N-myc and suppression of Akt/mTOR/NF-κB activation.

Subramanian C, Grogan PT, Opipari VP, Timmermann BN, Cohen MS. Subramanian C, et al. Among authors: grogan pt. Oncotarget. 2018 Feb 7;9(18):14509-14523. doi: 10.18632/oncotarget.24429. eCollection 2018 Mar 6. Oncotarget. 2018. PMID: 29581860 Free PMC article.

4

Cytotoxicity of withaferin A in glioblastomas involves induction of an oxidative stress-mediated heat shock response while altering Akt/mTOR and MAPK signaling pathways.

Grogan PT, Sleder KD, Samadi AK, Zhang H, Timmermann BN, Cohen MS. Grogan PT, et al. Invest New Drugs. 2013 Jun;31(3):545-57. doi: 10.1007/s10637-012-9888-5. Epub 2012 Nov 6. Invest New Drugs. 2013. PMID: 23129310 Free PMC article.

5

Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation.

Grogan PT, Sarkaria JN, Timmermann BN, Cohen MS. Grogan PT, et al. Invest New Drugs. 2014 Aug;32(4):604-17. doi: 10.1007/s10637-014-0084-7. Epub 2014 Apr 10. Invest New Drugs. 2014. PMID: 24718901 Free PMC article.

6

Triazole Containing Novobiocin and Biphenyl Amides as Hsp90 C-Terminal Inhibitors.

Zhao J, Zhao H, Hall JA, Brown D, Brandes E, Bazzill J, Grogan PT, Subramanian C, Vielhauer G, Cohen MS, Blagg BS. Zhao J, et al. Among authors: grogan pt. Medchemcomm. 2014 Sep 1;5(9):1317-1323. doi: 10.1039/C4MD00102H. Medchemcomm. 2014. PMID: 25328661 Free PMC article.

7

Effects of peritumoral nanoconjugated cisplatin on laryngeal cancer stem cells.

Sim MW, Grogan PT, Subramanian C, Bradford CR, Carey TE, Forrest ML, Prince ME, Cohen MS. Sim MW, et al. Among authors: grogan pt. Laryngoscope. 2016 May;126(5):E184-90. doi: 10.1002/lary.25808. Epub 2015 Dec 21. Laryngoscope. 2016. PMID: 26690734 Free PMC article.

8

Novel C-terminal heat shock protein 90 inhibitors target breast cancer stem cells and block migration, self-renewal, and epithelial-mesenchymal transition.

Subramanian C, Grogan PT, Wang T, Bazzill J, Zuo A, White PT, Kalidindi A, Kuszynski D, Wang G, Blagg BSJ, Cohen MS. Subramanian C, et al. Among authors: grogan pt. Mol Oncol. 2020 Sep;14(9):2058-2068. doi: 10.1002/1878-0261.12686. Epub 2020 May 15. Mol Oncol. 2020. PMID: 32255264 Free PMC article.

9

Growth of melanoma brain tumors monitored by photoacoustic microscopy.

Staley J, Grogan P, Samadi AK, Cui H, Cohen MS, Yang X. Staley J, et al. J Biomed Opt. 2010 Jul-Aug;15(4):040510. doi: 10.1117/1.3478309. J Biomed Opt. 2010. PMID: 20799777 Free article.

10

Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts.

Kitange GJ, Carlson BL, Schroeder MA, Grogan PT, Lamont JD, Decker PA, Wu W, James CD, Sarkaria JN. Kitange GJ, et al. Among authors: grogan pt. Neuro Oncol. 2009 Jun;11(3):281-91. doi: 10.1215/15228517-2008-090. Epub 2008 Oct 24. Neuro Oncol. 2009. PMID: 18952979 Free PMC article.

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