Gazit E - Search Results

1

Methylations of tryptophan-modified naphthoquinone affect its inhibitory potential toward Aβ aggregation.

Scherzer-Attali R, Convertino M, Pellarin R, Gazit E, Segal D, Caflisch A. Scherzer-Attali R, et al. Among authors: gazit e. J Phys Chem B. 2013 Feb 14;117(6):1780-9. doi: 10.1021/jp309066p. Epub 2013 Jan 31. J Phys Chem B. 2013. PMID: 23259849

2

Mechanistic studies of the process of amyloid fibrils formation by the use of peptide fragments and analogues: implications for the design of fibrillization inhibitors.

Gazit E. Gazit E. Curr Med Chem. 2002 Oct;9(19):1725-35. doi: 10.2174/0929867023369187. Curr Med Chem. 2002. PMID: 12369883 Review.

3

Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism.

Porat Y, Abramowitz A, Gazit E. Porat Y, et al. Among authors: gazit e. Chem Biol Drug Des. 2006 Jan;67(1):27-37. doi: 10.1111/j.1747-0285.2005.00318.x. Chem Biol Drug Des. 2006. PMID: 16492146 Review.

4

Inhibition of amyloid fibril formation and cytotoxicity by hydroxyindole derivatives.

Cohen T, Frydman-Marom A, Rechter M, Gazit E. Cohen T, et al. Among authors: gazit e. Biochemistry. 2006 Apr 18;45(15):4727-35. doi: 10.1021/bi051525c. Biochemistry. 2006. PMID: 16605241

5

Cognitive-performance recovery of Alzheimer's disease model mice by modulation of early soluble amyloidal assemblies.

Frydman-Marom A, Rechter M, Shefler I, Bram Y, Shalev DE, Gazit E. Frydman-Marom A, et al. Among authors: gazit e. Angew Chem Int Ed Engl. 2009;48(11):1981-6. doi: 10.1002/anie.200802123. Angew Chem Int Ed Engl. 2009. PMID: 19035593

6

Complete phenotypic recovery of an Alzheimer's disease model by a quinone-tryptophan hybrid aggregation inhibitor.

Scherzer-Attali R, Pellarin R, Convertino M, Frydman-Marom A, Egoz-Matia N, Peled S, Levy-Sakin M, Shalev DE, Caflisch A, Gazit E, Segal D. Scherzer-Attali R, et al. Among authors: gazit e. PLoS One. 2010 Jun 14;5(6):e11101. doi: 10.1371/journal.pone.0011101. PLoS One. 2010. PMID: 20559435 Free PMC article.

7

Inhibiting α-synuclein oligomerization by stable cell-penetrating β-synuclein fragments recovers phenotype of Parkinson's disease model flies.

Shaltiel-Karyo R, Frenkel-Pinter M, Egoz-Matia N, Frydman-Marom A, Shalev DE, Segal D, Gazit E. Shaltiel-Karyo R, et al. Among authors: gazit e. PLoS One. 2010 Nov 10;5(11):e13863. doi: 10.1371/journal.pone.0013863. PLoS One. 2010. PMID: 21085664 Free PMC article.

8

Targeting insulin amyloid assembly by small aromatic molecules: toward rational design of aggregation inhibitors.

Levy-Sakin M, Shreberk M, Daniel Y, Gazit E. Levy-Sakin M, et al. Among authors: gazit e. Islets. 2009 Nov-Dec;1(3):210-5. doi: 10.4161/isl.1.3.9609. Islets. 2009. PMID: 21099274 Free article.

9

Quantitative structure-activity relationship analysis of β-amyloid aggregation inhibitors.

Stempler S, Levy-Sakin M, Frydman-Marom A, Amir Y, Scherzer-Attali R, Buzhansky L, Gazit E, Senderowitz H. Stempler S, et al. Among authors: gazit e. J Comput Aided Mol Des. 2011 Feb;25(2):135-44. doi: 10.1007/s10822-010-9405-x. Epub 2010 Dec 17. J Comput Aided Mol Des. 2011. PMID: 21165759

10

Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models.

Frydman-Marom A, Levin A, Farfara D, Benromano T, Scherzer-Attali R, Peled S, Vassar R, Segal D, Gazit E, Frenkel D, Ovadia M. Frydman-Marom A, et al. Among authors: gazit e. PLoS One. 2011 Jan 28;6(1):e16564. doi: 10.1371/journal.pone.0016564. PLoS One. 2011. PMID: 21305046 Free PMC article.

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