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Overexpression of HMGB1 in melanoma predicts patient survival and suppression of HMGB1 induces cell cycle arrest and senescence in association with p21 (Waf1/Cip1) up-regulation via a p53-independent, Sp1-dependent pathway.
Li Q, Li J, Wen T, Zeng W, Peng C, Yan S, Tan J, Yang K, Liu S, Guo A, Zhang C, Su J, Jiang M, Liu Z, Zhou H, Chen X. Li Q, et al. Among authors: chen x. Oncotarget. 2014 Aug 15;5(15):6387-403. doi: 10.18632/oncotarget.2201. Oncotarget. 2014. PMID: 25051367 Free PMC article.
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