Detorio MA - Search Results

1

Cellular pharmacology and potency of HIV-1 nucleoside analogs in primary human macrophages.

Gavegnano C, Detorio MA, Bassit L, Hurwitz SJ, North TW, Schinazi RF. Gavegnano C, et al. Among authors: detorio ma. Antimicrob Agents Chemother. 2013 Mar;57(3):1262-9. doi: 10.1128/AAC.02012-12. Epub 2012 Dec 21. Antimicrob Agents Chemother. 2013. PMID: 23263005 Free PMC article.

2

Selection and characterization of HIV-1 with a novel S68 deletion in reverse transcriptase.

Schinazi RF, Massud I, Rapp KL, Cristiano M, Detorio MA, Stanton RA, Bennett MA, Kierlin-Duncan M, Lennerstrand J, Nettles JH. Schinazi RF, et al. Among authors: detorio ma. Antimicrob Agents Chemother. 2011 May;55(5):2054-60. doi: 10.1128/AAC.01700-10. Epub 2011 Feb 28. Antimicrob Agents Chemother. 2011. PMID: 21357304 Free PMC article.

3

Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.

Sluis-Cremer N, Koontz D, Bassit L, Hernandez-Santiago BI, Detorio M, Rapp KL, Amblard F, Bondada L, Grier J, Coats SJ, Schinazi RF, Mellors JW. Sluis-Cremer N, et al. Antimicrob Agents Chemother. 2009 Sep;53(9):3715-9. doi: 10.1128/AAC.00392-09. Epub 2009 Jul 13. Antimicrob Agents Chemother. 2009. PMID: 19596885 Free PMC article.

4

Ruxolitinib and tofacitinib are potent and selective inhibitors of HIV-1 replication and virus reactivation in vitro.

Gavegnano C, Detorio M, Montero C, Bosque A, Planelles V, Schinazi RF. Gavegnano C, et al. Antimicrob Agents Chemother. 2014;58(4):1977-86. doi: 10.1128/AAC.02496-13. Epub 2014 Jan 13. Antimicrob Agents Chemother. 2014. PMID: 24419350 Free PMC article.

5

Synthesis and antiviral evaluation of 2-amino-6-carbamoylpurine dioxolane nucleoside derivatives and their phosphoramidates prodrugs.

Cho JH, Bondana L, Detorio MA, Montero C, Bassit LC, Amblard F, Coats SJ, Schinazi RF. Cho JH, et al. Among authors: detorio ma. Bioorg Med Chem. 2014 Dec 1;22(23):6665-6671. doi: 10.1016/j.bmc.2014.10.003. Epub 2014 Oct 13. Bioorg Med Chem. 2014. PMID: 25458500 Free PMC article.

6

Synthesis and evaluation of 3'-azido-2',3'-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus.

Zhang HW, Coats SJ, Bondada L, Amblard F, Detorio M, Asif G, Fromentin E, Solomon S, Obikhod A, Whitaker T, Sluis-Cremer N, Mellors JW, Schinazi RF. Zhang HW, et al. Bioorg Med Chem Lett. 2010 Jan 1;20(1):60-4. doi: 10.1016/j.bmcl.2009.11.031. Epub 2009 Nov 13. Bioorg Med Chem Lett. 2010. PMID: 19948402 Free PMC article.

7

The base component of 3'-azido-2',3'-dideoxynucleosides influences resistance mutations selected in HIV-1 reverse transcriptase.

Meteer JD, Koontz D, Asif G, Zhang HW, Detorio M, Solomon S, Coats SJ, Sluis-Cremer N, Schinazi RF, Mellors JW. Meteer JD, et al. Antimicrob Agents Chemother. 2011 Aug;55(8):3758-64. doi: 10.1128/AAC.00414-11. Epub 2011 Jun 6. Antimicrob Agents Chemother. 2011. PMID: 21646480 Free PMC article.

8

Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3'-azido-2',3'-dideoxypurine nucleosides.

Zhang HW, Detorio M, Herman BD, Solomon S, Bassit L, Nettles JH, Obikhod A, Tao SJ, Mellors JW, Sluis-Cremer N, Coats SJ, Schinazi RF. Zhang HW, et al. Eur J Med Chem. 2011 Sep;46(9):3832-44. doi: 10.1016/j.ejmech.2011.05.051. Epub 2011 May 30. Eur J Med Chem. 2011. PMID: 21700368 Free PMC article.

9

Universal profiling of HIV-1 pol for genotypic study and resistance analysis across subtypes.

Nie T, Detorio M, Schinazi RF. Nie T, et al. Antivir Ther. 2011;16(8):1267-75. doi: 10.3851/IMP1892. Antivir Ther. 2011. PMID: 22155908 Free PMC article.

10

Adenosine Dioxolane Nucleoside Phosphoramidates as Antiviral Agents for Human Immunodeficiency and Hepatitis B Viruses.

Bondada L, Detorio M, Bassit L, Tao S, Montero CM, Singletary TM, Zhang H, Zhou L, Cho JH, Coats SJ, Schinazi RF. Bondada L, et al. ACS Med Chem Lett. 2013 Aug 8;4(8):747-751. doi: 10.1021/ml4001497. ACS Med Chem Lett. 2013. PMID: 24015326 Free PMC article.

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