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Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts.
Lawley TD, Clare S, Walker AW, Goulding D, Stabler RA, Croucher N, Mastroeni P, Scott P, Raisen C, Mottram L, Fairweather NF, Wren BW, Parkhill J, Dougan G. Lawley TD, et al. Among authors: walker aw. Infect Immun. 2009 Sep;77(9):3661-9. doi: 10.1128/IAI.00558-09. Epub 2009 Jun 29. Infect Immun. 2009. PMID: 19564382 Free PMC article.
Therapeutic modulation of intestinal dysbiosis.
Walker AW, Lawley TD. Walker AW, et al. Pharmacol Res. 2013 Mar;69(1):75-86. doi: 10.1016/j.phrs.2012.09.008. Epub 2012 Sep 24. Pharmacol Res. 2013. PMID: 23017673 Review.
Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice.
Lawley TD, Clare S, Walker AW, Stares MD, Connor TR, Raisen C, Goulding D, Rad R, Schreiber F, Brandt C, Deakin LJ, Pickard DJ, Duncan SH, Flint HJ, Clark TG, Parkhill J, Dougan G. Lawley TD, et al. Among authors: walker aw. PLoS Pathog. 2012;8(10):e1002995. doi: 10.1371/journal.ppat.1002995. Epub 2012 Oct 25. PLoS Pathog. 2012. PMID: 23133377 Free PMC article.
Intestinal colonization resistance.
Lawley TD, Walker AW. Lawley TD, et al. Among authors: walker aw. Immunology. 2013 Jan;138(1):1-11. doi: 10.1111/j.1365-2567.2012.03616.x. Immunology. 2013. PMID: 23240815 Free PMC article. Review.
The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.
Zaiss MM, Rapin A, Lebon L, Dubey LK, Mosconi I, Sarter K, Piersigilli A, Menin L, Walker AW, Rougemont J, Paerewijck O, Geldhof P, McCoy KD, Macpherson AJ, Croese J, Giacomin PR, Loukas A, Junt T, Marsland BJ, Harris NL. Zaiss MM, et al. Among authors: walker aw. Immunity. 2015 Nov 17;43(5):998-1010. doi: 10.1016/j.immuni.2015.09.012. Epub 2015 Oct 27. Immunity. 2015. PMID: 26522986 Free PMC article.
Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies.
Kennedy KM, de Goffau MC, Perez-Muñoz ME, Arrieta MC, Bäckhed F, Bork P, Braun T, Bushman FD, Dore J, de Vos WM, Earl AM, Eisen JA, Elovitz MA, Ganal-Vonarburg SC, Gänzle MG, Garrett WS, Hall LJ, Hornef MW, Huttenhower C, Konnikova L, Lebeer S, Macpherson AJ, Massey RC, McHardy AC, Koren O, Lawley TD, Ley RE, O'Mahony L, O'Toole PW, Pamer EG, Parkhill J, Raes J, Rattei T, Salonen A, Segal E, Segata N, Shanahan F, Sloboda DM, Smith GCS, Sokol H, Spector TD, Surette MG, Tannock GW, Walker AW, Yassour M, Walter J. Kennedy KM, et al. Among authors: walker aw. Nature. 2023 Jan;613(7945):639-649. doi: 10.1038/s41586-022-05546-8. Epub 2023 Jan 25. Nature. 2023. PMID: 36697862 Free PMC article. Review.
143 results