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The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.
Blanc M, Hsieh WY, Robertson KA, Kropp KA, Forster T, Shui G, Lacaze P, Watterson S, Griffiths SJ, Spann NJ, Meljon A, Talbot S, Krishnan K, Covey DF, Wenk MR, Craigon M, Ruzsics Z, Haas J, Angulo A, Griffiths WJ, Glass CK, Wang Y, Ghazal P. Blanc M, et al. Immunity. 2013 Jan 24;38(1):106-18. doi: 10.1016/j.immuni.2012.11.004. Epub 2012 Dec 27. Immunity. 2013. PMID: 23273843 Free PMC article.
Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-γ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral state.
Kropp KA, Robertson KA, Sing G, Rodriguez-Martin S, Blanc M, Lacaze P, Hassim MF, Khondoker MR, Busche A, Dickinson P, Forster T, Strobl B, Mueller M, Jonjic S, Angulo A, Ghazal P. Kropp KA, et al. Among authors: blanc m. J Virol. 2011 Oct;85(19):10286-99. doi: 10.1128/JVI.00373-11. Epub 2011 Jul 20. J Virol. 2011. PMID: 21775459 Free PMC article.
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis.
Blanc M, Hsieh WY, Robertson KA, Watterson S, Shui G, Lacaze P, Khondoker M, Dickinson P, Sing G, Rodríguez-Martín S, Phelan P, Forster T, Strobl B, Müller M, Riemersma R, Osborne T, Wenk MR, Angulo A, Ghazal P. Blanc M, et al. PLoS Biol. 2011 Mar;9(3):e1000598. doi: 10.1371/journal.pbio.1000598. Epub 2011 Mar 8. PLoS Biol. 2011. PMID: 21408089 Free PMC article.
Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection.
Rodríguez-Martín S, Kropp KA, Wilhelmi V, Lisnic VJ, Hsieh WY, Blanc M, Livingston A, Busche A, Tekotte H, Messerle M, Auer M, Fraser I, Jonjic S, Angulo A, Reddehase MJ, Ghazal P. Rodríguez-Martín S, et al. Among authors: blanc m. PLoS Pathog. 2012;8(8):e1002901. doi: 10.1371/journal.ppat.1002901. Epub 2012 Aug 30. PLoS Pathog. 2012. PMID: 22952450 Free PMC article.
An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway.
Robertson KA, Hsieh WY, Forster T, Blanc M, Lu H, Crick PJ, Yutuc E, Watterson S, Martin K, Griffiths SJ, Enright AJ, Yamamoto M, Pradeepa MM, Lennox KA, Behlke MA, Talbot S, Haas J, Dölken L, Griffiths WJ, Wang Y, Angulo A, Ghazal P. Robertson KA, et al. Among authors: blanc m. PLoS Biol. 2016 Mar 3;14(3):e1002364. doi: 10.1371/journal.pbio.1002364. eCollection 2016 Mar. PLoS Biol. 2016. PMID: 26938778 Free PMC article.
Palmitoylation, pathogens and their host.
Blanc M, Blaskovic S, van der Goot FG. Blanc M, et al. Biochem Soc Trans. 2013 Feb 1;41(1):84-8. doi: 10.1042/BST20120337. Biochem Soc Trans. 2013. PMID: 23356263 Review.
What does S-palmitoylation do to membrane proteins?
Blaskovic S, Blanc M, van der Goot FG. Blaskovic S, et al. Among authors: blanc m. FEBS J. 2013 Jun;280(12):2766-74. doi: 10.1111/febs.12263. Epub 2013 Apr 18. FEBS J. 2013. PMID: 23551889 Free article. Review.
SwissPalm 2: Protein S-Palmitoylation Database.
Blanc M, David FPA, van der Goot FG. Blanc M, et al. Methods Mol Biol. 2019;2009:203-214. doi: 10.1007/978-1-4939-9532-5_16. Methods Mol Biol. 2019. PMID: 31152406
577 results