Mielke H - Search Results

1

Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes.

Schug M, Stöber R, Heise T, Mielke H, Gundert-Remy U, Godoy P, Reif R, Blaszkewicz M, Ellinger-Ziegelbauer H, Ahr HJ, Selinski S, Günther G, Marchan R, Blaszkewicz M, Sachinidis A, Nüssler A, Oberemm A, Hengstler JG. Schug M, et al. Among authors: mielke h. Arch Toxicol. 2013 Feb;87(2):337-45. doi: 10.1007/s00204-012-0999-8. Epub 2012 Dec 29. Arch Toxicol. 2013. PMID: 23274394

2

Elevated internal exposure of children in simulated acute inhalation of volatile organic compounds: effects of concentration and duration.

Abraham K, Mielke H, Huisinga W, Gundert-Remy U. Abraham K, et al. Among authors: mielke h. Arch Toxicol. 2005 Feb;79(2):63-73. doi: 10.1007/s00204-004-0599-3. Epub 2004 Nov 25. Arch Toxicol. 2005. PMID: 15565428

3

Internal exposure of children by simulated acute inhalation of volatile organic compounds: the influence of chemical properties on the child/adult concentration ratio.

Abraham K, Mielke H, Huisinga W, Gundert-Remy U. Abraham K, et al. Among authors: mielke h. Basic Clin Pharmacol Toxicol. 2005 Mar;96(3):242-3. doi: 10.1111/j.1742-7843.2005.pto960315.x. Basic Clin Pharmacol Toxicol. 2005. PMID: 15733221 Free article. No abstract available.

4

Acute inhalative exposure assessment: derivation of guideline levels with special regard to sensitive subpopulations and time scaling.

Mielke H, Gundert A, Abraham K, Gundert-Remy U. Mielke H, et al. Toxicology. 2005 Oct 30;214(3):256-67. doi: 10.1016/j.tox.2005.06.018. Epub 2005 Aug 1. Toxicology. 2005. PMID: 16055256

5

Bisphenol A levels in blood depend on age and exposure.

Mielke H, Gundert-Remy U. Mielke H, et al. Toxicol Lett. 2009 Oct 8;190(1):32-40. doi: 10.1016/j.toxlet.2009.06.861. Epub 2009 Jun 26. Toxicol Lett. 2009. PMID: 19560527

6

A physiologically based toxicokinetic modelling approach to predict relevant concentrations for in vitro testing.

Mielke H, Anger LT, Schug M, Hengstler JG, Stahlmann R, Gundert-Remy U. Mielke H, et al. Arch Toxicol. 2011 Jun;85(6):555-63. doi: 10.1007/s00204-010-0612-y. Epub 2010 Nov 3. Arch Toxicol. 2011. PMID: 21046363

7

Physiologically based toxicokinetic modelling as a tool to assess target organ toxicity in route-to-route extrapolation--the case of coumarin.

Mielke H, Abraham K, Götz M, Vieth B, Lampen A, Luch A, Gundert-Remy U. Mielke H, et al. Toxicol Lett. 2011 Apr 25;202(2):100-10. doi: 10.1016/j.toxlet.2011.01.022. Epub 2011 Feb 1. Toxicol Lett. 2011. PMID: 21291965

8

The contribution of dermal exposure to the internal exposure of bisphenol A in man.

Mielke H, Partosch F, Gundert-Remy U. Mielke H, et al. Toxicol Lett. 2011 Jul 28;204(2-3):190-8. doi: 10.1016/j.toxlet.2011.04.032. Epub 2011 May 5. Toxicol Lett. 2011. PMID: 21571050

9

In vitro - in vivo correlation of gene expression alterations induced by liver carcinogens.

Heise T, Schug M, Storm D, Ellinger-Ziegelbauer H, Ahr HJ, Hellwig B, Rahnenfuhrer J, Ghallab A, Guenther G, Sisnaiske J, Reif R, Godoy P, Mielke H, Gundert-Remy U, Lampen A, Oberemm A, Hengstler JG. Heise T, et al. Among authors: mielke h. Curr Med Chem. 2012;19(11):1721-30. doi: 10.2174/092986712799945049. Curr Med Chem. 2012. PMID: 22414088

10

Physiologically based toxicokinetic modelling as a tool to support risk assessment: three case studies.

Mielke H, Gundert-Remy U. Mielke H, et al. J Toxicol. 2012;2012:359471. doi: 10.1155/2012/359471. Epub 2012 May 9. J Toxicol. 2012. PMID: 22649449 Free PMC article.

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