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Improved human bioavailability of vemurafenib, a practically insoluble drug, using an amorphous polymer-stabilized solid dispersion prepared by a solvent-controlled coprecipitation process.
Shah N, Iyer RM, Mair HJ, Choi DS, Tian H, Diodone R, Fähnrich K, Pabst-Ravot A, Tang K, Scheubel E, Grippo JF, Moreira SA, Go Z, Mouskountakis J, Louie T, Ibrahim PN, Sandhu H, Rubia L, Chokshi H, Singhal D, Malick W. Shah N, et al. Among authors: fahnrich k. J Pharm Sci. 2013 Mar;102(3):967-81. doi: 10.1002/jps.23425. Epub 2012 Dec 29. J Pharm Sci. 2013. PMID: 23280631