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The endocannabinoid N-arachidonoyl dopamine (NADA) selectively induces oxidative stress-mediated cell death in hepatic stellate cells but not in hepatocytes.
Wojtalla A, Herweck F, Granzow M, Klein S, Trebicka J, Huss S, Lerner R, Lutz B, Schildberg FA, Knolle PA, Sauerbruch T, Singer MV, Zimmer A, Siegmund SV. Wojtalla A, et al. Among authors: lerner r. Am J Physiol Gastrointest Liver Physiol. 2012 Apr 15;302(8):G873-87. doi: 10.1152/ajpgi.00241.2011. Epub 2012 Feb 2. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22301114 Free article.
Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor.
Pamplona FA, Ferreira J, Menezes de Lima O Jr, Duarte FS, Bento AF, Forner S, Villarinho JG, Bellocchio L, Wotjak CT, Lerner R, Monory K, Lutz B, Canetti C, Matias I, Calixto JB, Marsicano G, Guimarães MZ, Takahashi RN. Pamplona FA, et al. Among authors: lerner r. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21134-9. doi: 10.1073/pnas.1202906109. Epub 2012 Nov 12. Proc Natl Acad Sci U S A. 2012. PMID: 23150578 Free PMC article.
Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction.
Wenzel D, Matthey M, Bindila L, Lerner R, Lutz B, Zimmer A, Fleischmann BK. Wenzel D, et al. Among authors: lerner r. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18710-5. doi: 10.1073/pnas.1308130110. Epub 2013 Oct 28. Proc Natl Acad Sci U S A. 2013. PMID: 24167249 Free PMC article.
Age-related changes in the endocannabinoid system in the mouse hippocampus.
Piyanova A, Lomazzo E, Bindila L, Lerner R, Albayram O, Ruhl T, Lutz B, Zimmer A, Bilkei-Gorzo A. Piyanova A, et al. Among authors: lerner r. Mech Ageing Dev. 2015 Sep;150:55-64. doi: 10.1016/j.mad.2015.08.005. Epub 2015 Aug 13. Mech Ageing Dev. 2015. PMID: 26278494
818 results