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Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.
Tai LM, Bilousova T, Jungbauer L, Roeske SK, Youmans KL, Yu C, Poon WW, Cornwell LB, Miller CA, Vinters HV, Van Eldik LJ, Fardo DW, Estus S, Bu G, Gylys KH, Ladu MJ. Tai LM, et al. J Biol Chem. 2013 Feb 22;288(8):5914-26. doi: 10.1074/jbc.M112.442103. Epub 2013 Jan 4. J Biol Chem. 2013. PMID: 23293020 Free PMC article.
Introducing Human APOE into Aβ Transgenic Mouse Models.
Tai LM, Youmans KL, Jungbauer L, Yu C, Ladu MJ. Tai LM, et al. Int J Alzheimers Dis. 2011;2011:810981. doi: 10.4061/2011/810981. Epub 2011 Oct 19. Int J Alzheimers Dis. 2011. PMID: 22028984 Free PMC article.
Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody.
Youmans KL, Tai LM, Kanekiyo T, Stine WB Jr, Michon SC, Nwabuisi-Heath E, Manelli AM, Fu Y, Riordan S, Eimer WA, Binder L, Bu G, Yu C, Hartley DM, LaDu MJ. Youmans KL, et al. Among authors: tai lm. Mol Neurodegener. 2012 Mar 16;7:8. doi: 10.1186/1750-1326-7-8. Mol Neurodegener. 2012. PMID: 22423893 Free PMC article.
64 results