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Human kallikrein overexpression alleviates cardiac aging by alternatively regulating macrophage polarization in aged rats.
Hu D, Dong R, Yang Y, Chen Z, Tang Y, Fu M, Wang DW, Xu X, Tu L. Hu D, et al. Among authors: yang y. FASEB J. 2019 Jul;33(7):8436-8452. doi: 10.1096/fj.201802371RR. Epub 2019 Apr 17. FASEB J. 2019. PMID: 30995868
Thus, hKLK1 overexpression reduced cardiac fibrosis and improved aging-related cardiac dysfunction through reduced shift of macrophages to M2 macrophages, indicating that hKLK1 may alleviate aging-related cardiac dysfunction.-Hu, D., Dong, R., Yang, Y., Chen, Z., Ta …
Thus, hKLK1 overexpression reduced cardiac fibrosis and improved aging-related cardiac dysfunction through reduced shift of macrophages to M …
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