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Page 1
Bioactive flavaglines and other constituents isolated from Aglaia perviridis.
Pan L, Acuña UM, Li J, Jena N, Ninh TN, Pannell CM, Chai H, Fuchs JR, Carcache de Blanco EJ, Soejarto DD, Kinghorn AD. Pan L, et al. Among authors: fuchs jr. J Nat Prod. 2013 Mar 22;76(3):394-404. doi: 10.1021/np3007588. Epub 2013 Jan 9. J Nat Prod. 2013. PMID: 23301897 Free PMC article.
Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors.
Kessl JJ, Jena N, Koh Y, Taskent-Sezgin H, Slaughter A, Feng L, de Silva S, Wu L, Le Grice SF, Engelman A, Fuchs JR, Kvaratskhelia M. Kessl JJ, et al. Among authors: fuchs jr. J Biol Chem. 2012 May 11;287(20):16801-11. doi: 10.1074/jbc.M112.354373. Epub 2012 Mar 21. J Biol Chem. 2012. PMID: 22437836 Free PMC article.
Use of the hollow fiber assay for the discovery of novel anticancer agents from fungi.
Pearce CJ, Lantvit DD, Shen Q, Jarjoura D, Zhang X, Oberlies NH, Kroll DJ, Wani MC, Orjala J, Soejarto DD, Farnsworth NR, de Blanco EJ, Fuchs JR, Kinghorn AD, Swanson SM. Pearce CJ, et al. Among authors: fuchs jr. Methods Mol Biol. 2012;944:267-77. doi: 10.1007/978-1-62703-122-6_20. Methods Mol Biol. 2012. PMID: 23065624
The A128T resistance mutation reveals aberrant protein multimerization as the primary mechanism of action of allosteric HIV-1 integrase inhibitors.
Feng L, Sharma A, Slaughter A, Jena N, Koh Y, Shkriabai N, Larue RC, Patel PA, Mitsuya H, Kessl JJ, Engelman A, Fuchs JR, Kvaratskhelia M. Feng L, et al. Among authors: fuchs jr. J Biol Chem. 2013 May 31;288(22):15813-20. doi: 10.1074/jbc.M112.443390. Epub 2013 Apr 24. J Biol Chem. 2013. PMID: 23615903 Free PMC article.
A new class of multimerization selective inhibitors of HIV-1 integrase.
Sharma A, Slaughter A, Jena N, Feng L, Kessl JJ, Fadel HJ, Malani N, Male F, Wu L, Poeschla E, Bushman FD, Fuchs JR, Kvaratskhelia M. Sharma A, et al. Among authors: fuchs jr. PLoS Pathog. 2014 May 29;10(5):e1004171. doi: 10.1371/journal.ppat.1004171. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24874515 Free PMC article.
Potent cytotoxic arylnaphthalene lignan lactones from Phyllanthus poilanei.
Ren Y, Lantvit DD, Deng Y, Kanagasabai R, Gallucci JC, Ninh TN, Chai HB, Soejarto DD, Fuchs JR, Yalowich JC, Yu J, Swanson SM, Kinghorn AD. Ren Y, et al. Among authors: fuchs jr. J Nat Prod. 2014 Jun 27;77(6):1494-504. doi: 10.1021/np5002785. Epub 2014 Jun 12. J Nat Prod. 2014. PMID: 24937209 Free PMC article.
153 results