El Khattabi I - Search Results

1

Thyroid hormone promotes postnatal rat pancreatic β-cell development and glucose-responsive insulin secretion through MAFA.

Aguayo-Mazzucato C, Zavacki AM, Marinelarena A, Hollister-Lock J, El Khattabi I, Marsili A, Weir GC, Sharma A, Larsen PR, Bonner-Weir S. Aguayo-Mazzucato C, et al. Among authors: el khattabi i. Diabetes. 2013 May;62(5):1569-80. doi: 10.2337/db12-0849. Epub 2013 Jan 10. Diabetes. 2013. PMID: 23305647 Free PMC article.

2

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells.

Aguayo-Mazzucato C, Koh A, El Khattabi I, Li WC, Toschi E, Jermendy A, Juhl K, Mao K, Weir GC, Sharma A, Bonner-Weir S. Aguayo-Mazzucato C, et al. Among authors: el khattabi i. Diabetologia. 2011 Mar;54(3):583-93. doi: 10.1007/s00125-010-2026-z. Epub 2010 Dec 29. Diabetologia. 2011. PMID: 21190012 Free PMC article.

3

A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells.

Nishimura W, Kondo T, Salameh T, El Khattabi I, Dodge R, Bonner-Weir S, Sharma A. Nishimura W, et al. Among authors: el khattabi i. Dev Biol. 2006 May 15;293(2):526-39. doi: 10.1016/j.ydbio.2006.02.028. Epub 2006 Apr 3. Dev Biol. 2006. PMID: 16580660 Free PMC article.

4

p38 MAPK is a major regulator of MafA protein stability under oxidative stress.

Kondo T, El Khattabi I, Nishimura W, Laybutt DR, Geraldes P, Shah S, King G, Bonner-Weir S, Weir G, Sharma A. Kondo T, et al. Among authors: el khattabi i. Mol Endocrinol. 2009 Aug;23(8):1281-90. doi: 10.1210/me.2008-0482. Epub 2009 Apr 30. Mol Endocrinol. 2009. PMID: 19407223 Free PMC article.

5

Preventing p38 MAPK-mediated MafA degradation ameliorates β-cell dysfunction under oxidative stress.

El Khattabi I, Sharma A. El Khattabi I, et al. Mol Endocrinol. 2013 Jul;27(7):1078-90. doi: 10.1210/me.2012-1346. Epub 2013 May 9. Mol Endocrinol. 2013. PMID: 23660596 Free PMC article.

6

Differentiation of pancreatic endocrine progenitors reversibly blocked by premature induction of MafA.

He KH, Juhl K, Karadimos M, El Khattabi I, Fitzpatrick C, Bonner-Weir S, Sharma A. He KH, et al. Among authors: el khattabi i. Dev Biol. 2014 Jan 1;385(1):2-12. doi: 10.1016/j.ydbio.2013.10.024. Epub 2013 Oct 29. Dev Biol. 2014. PMID: 24183936 Free PMC article.

7

Proper activation of MafA is required for optimal differentiation and maturation of pancreatic β-cells.

El Khattabi I, Sharma A. El Khattabi I, et al. Best Pract Res Clin Endocrinol Metab. 2015 Dec;29(6):821-31. doi: 10.1016/j.beem.2015.09.006. Epub 2015 Oct 9. Best Pract Res Clin Endocrinol Metab. 2015. PMID: 26696512 Free PMC article. Review.

8

β-cell preservation and regeneration for diabetes treatment: where are we now?

Karadimos MJ, Kapoor A, El Khattabi I, Sharma A. Karadimos MJ, et al. Among authors: el khattabi i. Diabetes Manag (Lond). 2012 May 1;2(3):213-222. doi: 10.2217/dmt.12.21. Diabetes Manag (Lond). 2012. PMID: 23049620 Free PMC article.

9

Compensatory Response by Late Embryonic Tubular Epithelium to the Reduction in Pancreatic Progenitors.

Nishimura W, Kapoor A, El Khattabi I, Jin W, Yasuda K, Bonner-Weir S, Sharma A. Nishimura W, et al. Among authors: el khattabi i. PLoS One. 2015 Nov 5;10(11):e0142286. doi: 10.1371/journal.pone.0142286. eCollection 2015. PLoS One. 2015. PMID: 26540252 Free PMC article.

10

Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice.

Kuznetsova A, Yu Y, Hollister-Lock J, Opare-Addo L, Rozzo A, Sadagurski M, Norquay L, Reed JE, El Khattabi I, Bonner-Weir S, Weir GC, Sharma A, White MF. Kuznetsova A, et al. Among authors: el khattabi i. JCI Insight. 2016;1(3):e80749. doi: 10.1172/jci.insight.80749. Epub 2016 Mar 17. JCI Insight. 2016. PMID: 27152363 Free PMC article.

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