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Page 1
Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria.
Zhang Q, Siegel TN, Martins RM, Wang F, Cao J, Gao Q, Cheng X, Jiang L, Hon CC, Scheidig-Benatar C, Sakamoto H, Turner L, Jensen AT, Claes A, Guizetti J, Malmquist NA, Scherf A. Zhang Q, et al. Among authors: malmquist na. Nature. 2014 Sep 18;513(7518):431-5. doi: 10.1038/nature13468. Epub 2014 Jun 29. Nature. 2014. PMID: 25043062
Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans.
Malmquist NA, Sundriyal S, Caron J, Chen P, Witkowski B, Menard D, Suwanarusk R, Renia L, Nosten F, Jiménez-Díaz MB, Angulo-Barturen I, Santos Martínez M, Ferrer S, Sanz LM, Gamo FJ, Wittlin S, Duffy S, Avery VM, Ruecker A, Delves MJ, Sinden RE, Fuchter MJ, Scherf A. Malmquist NA, et al. Antimicrob Agents Chemother. 2015 Feb;59(2):950-9. doi: 10.1128/AAC.04419-14. Epub 2014 Nov 24. Antimicrob Agents Chemother. 2015. PMID: 25421480 Free PMC article.
Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures.
Dembélé L, Franetich JF, Lorthiois A, Gego A, Zeeman AM, Kocken CH, Le Grand R, Dereuddre-Bosquet N, van Gemert GJ, Sauerwein R, Vaillant JC, Hannoun L, Fuchter MJ, Diagana TT, Malmquist NA, Scherf A, Snounou G, Mazier D. Dembélé L, et al. Among authors: malmquist na. Nat Med. 2014 Mar;20(3):307-12. doi: 10.1038/nm.3461. Epub 2014 Feb 9. Nat Med. 2014. PMID: 24509527
Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).
Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YL. Lucas-Hourani M, et al. Among authors: malmquist na. J Med Chem. 2015 Jul 23;58(14):5579-98. doi: 10.1021/acs.jmedchem.5b00606. Epub 2015 Jun 30. J Med Chem. 2015. PMID: 26079043 Free PMC article.
23 results