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Antibodies to Escherichia coli-expressed C-terminal domains of Plasmodium falciparum variant surface antigen 2-chondroitin sulfate A (VAR2CSA) inhibit binding of CSA-adherent parasites to placental tissue.
Saveria T, Oleinikov AV, Wiliamson K, Chaturvedi R, Lograsso J, Keitany GJ, Fried M, Duffy P. Saveria T, et al. Among authors: oleinikov av. Infect Immun. 2013 Apr;81(4):1031-9. doi: 10.1128/IAI.00978-12. Epub 2013 Jan 14. Infect Immun. 2013. PMID: 23319559 Free PMC article.
An Invariant Protein That Colocalizes With VAR2CSA on Plasmodium falciparum-Infected Red Cells Binds to Chondroitin Sulfate A.
Keitany GJ, Jenkins BJ, Obiakor HT, Daniel S, Muehlenbachs A, Semblat JP, Gamain B, Doritchamou JYA, Desai SA, MacDonald NJ, Narum DL, Morrison R, Saveria T, Vignali M, Oleinikov AV, Fried M, Duffy PE. Keitany GJ, et al. Among authors: oleinikov av. J Infect Dis. 2022 Jun 1;225(11):2011-2022. doi: 10.1093/infdis/jiab550. J Infect Dis. 2022. PMID: 34718641 Free PMC article.
High throughput functional assays of the variant antigen PfEMP1 reveal a single domain in the 3D7 Plasmodium falciparum genome that binds ICAM1 with high affinity and is targeted by naturally acquired neutralizing antibodies.
Oleinikov AV, Amos E, Frye IT, Rossnagle E, Mutabingwa TK, Fried M, Duffy PE. Oleinikov AV, et al. PLoS Pathog. 2009 Apr;5(4):e1000386. doi: 10.1371/journal.ppat.1000386. Epub 2009 Apr 17. PLoS Pathog. 2009. PMID: 19381252 Free PMC article.
Multilaboratory approach to preclinical evaluation of vaccine immunogens for placental malaria.
Fried M, Avril M, Chaturvedi R, Fernandez P, Lograsso J, Narum D, Nielsen MA, Oleinikov AV, Resende M, Salanti A, Saveria T, Williamson K, Dicko A, Scherf A, Smith JD, Theander TG, Duffy PE. Fried M, et al. Among authors: oleinikov av. Infect Immun. 2013 Feb;81(2):487-95. doi: 10.1128/IAI.01106-12. Epub 2012 Dec 3. Infect Immun. 2013. PMID: 23208604 Free PMC article.
Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria.
Raj DK, Das Mohapatra A, Jnawali A, Zuromski J, Jha A, Cham-Kpu G, Sherman B, Rudlaff RM, Nixon CE, Hilton N, Oleinikov AV, Chesnokov O, Merritt J, Pond-Tor S, Burns L, Jolly G, Ben Mamoun C, Kabyemela E, Muehlenbachs A, Lambert L, Orr-Gonzalez S, Gnädig NF, Fidock DA, Park S, Dvorin JD, Pardi N, Weissman D, Mui BL, Tam YK, Friedman JF, Fried M, Duffy PE, Kurtis JD. Raj DK, et al. Among authors: oleinikov av. Nature. 2020 Jun;582(7810):104-108. doi: 10.1038/s41586-020-2220-1. Epub 2020 Apr 22. Nature. 2020. PMID: 32427965 Free PMC article.
57 results