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Mapping the glycoprotein Ib-binding site in the von willebrand factor A1 domain.
Cruz MA, Diacovo TG, Emsley J, Liddington R, Handin RI. Cruz MA, et al. Among authors: emsley j. J Biol Chem. 2000 Jun 23;275(25):19098-105. doi: 10.1074/jbc.M002292200. J Biol Chem. 2000. PMID: 10764791 Free article.
Based on the crystal structure of the vWF-A1 domain (Emsley, J., Cruz, M., Handin, R., and Liddington, R. (1998) J. Biol. Chem. 273, 10396-10401), we introduced point mutations into 16 candidate residues that might form all or part of the GPIb interaction sit …
Based on the crystal structure of the vWF-A1 domain (Emsley, J., Cruz, M., Handin, R., and Liddington, R. (1998) J. Bio …
183 results