Malliri A - Search Results

1

Constitutive RAC activation is not sufficient to initiate melanocyte neoplasia but accelerates malignant progression.

Dalton LE, Kamarashev J, Barinaga-Rementeria Ramirez I, White G, Malliri A, Hurlstone A. Dalton LE, et al. Among authors: malliri a. J Invest Dermatol. 2013 Jun;133(6):1572-81. doi: 10.1038/jid.2013.23. Epub 2013 Jan 21. J Invest Dermatol. 2013. PMID: 23337888 Free article.

2

The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells.

Malliri A, Symons M, Hennigan RF, Hurlstone AF, Lamb RF, Wheeler T, Ozanne BW. Malliri A, et al. J Cell Biol. 1998 Nov 16;143(4):1087-99. doi: 10.1083/jcb.143.4.1087. J Cell Biol. 1998. PMID: 9817764 Free PMC article.

3

The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.

Malliri A, Rygiel TP, van der Kammen RA, Song JY, Engers R, Hurlstone AF, Clevers H, Collard JG. Malliri A, et al. J Biol Chem. 2006 Jan 6;281(1):543-8. doi: 10.1074/jbc.M507582200. Epub 2005 Oct 25. J Biol Chem. 2006. PMID: 16249175 Free article.

4

SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1.

Woodcock SA, Rooney C, Liontos M, Connolly Y, Zoumpourlis V, Whetton AD, Gorgoulis VG, Malliri A. Woodcock SA, et al. Among authors: malliri a. Mol Cell. 2009 Mar 13;33(5):639-53. doi: 10.1016/j.molcel.2009.02.012. Mol Cell. 2009. PMID: 19285946 Free article.

5

The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly.

Rooney C, White G, Nazgiewicz A, Woodcock SA, Anderson KI, Ballestrem C, Malliri A. Rooney C, et al. Among authors: malliri a. EMBO Rep. 2010 Apr;11(4):292-8. doi: 10.1038/embor.2010.10. Epub 2010 Mar 12. EMBO Rep. 2010. PMID: 20224579 Free PMC article.

6

Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression.

Woodcock SA, Rushton HJ, Castañeda-Saucedo E, Myant K, White GR, Blyth K, Sansom OJ, Malliri A. Woodcock SA, et al. Among authors: malliri a. Curr Biol. 2010 Apr 13;20(7):669-75. doi: 10.1016/j.cub.2010.02.033. Epub 2010 Mar 25. Curr Biol. 2010. PMID: 20346677 Free PMC article.

7

The diverse roles of Rac signaling in tumorigenesis.

Mack NA, Whalley HJ, Castillo-Lluva S, Malliri A. Mack NA, et al. Among authors: malliri a. Cell Cycle. 2011 May 15;10(10):1571-81. doi: 10.4161/cc.10.10.15612. Epub 2011 May 15. Cell Cycle. 2011. PMID: 21478669 Free PMC article. Review.

8

The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation.

Castillo-Lluva S, Tan CT, Daugaard M, Sorensen PH, Malliri A. Castillo-Lluva S, et al. Among authors: malliri a. Oncogene. 2013 Mar 28;32(13):1735-42. doi: 10.1038/onc.2012.189. Epub 2012 May 21. Oncogene. 2013. PMID: 22614015

9

β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity.

Mack NA, Porter AP, Whalley HJ, Schwarz JP, Jones RC, Khaja AS, Bjartell A, Anderson KI, Malliri A. Mack NA, et al. Among authors: malliri a. Nat Cell Biol. 2012 Nov;14(11):1169-80. doi: 10.1038/ncb2608. Epub 2012 Oct 28. Nat Cell Biol. 2012. PMID: 23103911 Free PMC article.

10

HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion.

Vaughan L, Tan CT, Chapman A, Nonaka D, Mack NA, Smith D, Booton R, Hurlstone AF, Malliri A. Vaughan L, et al. Among authors: malliri a. Cell Rep. 2015 Jan 6;10(1):88-102. doi: 10.1016/j.celrep.2014.12.012. Epub 2014 Dec 24. Cell Rep. 2015. PMID: 25543140 Free PMC article.

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