White G - Search Results

1

Constitutive RAC activation is not sufficient to initiate melanocyte neoplasia but accelerates malignant progression.

Dalton LE, Kamarashev J, Barinaga-Rementeria Ramirez I, White G, Malliri A, Hurlstone A. Dalton LE, et al. Among authors: white g. J Invest Dermatol. 2013 Jun;133(6):1572-81. doi: 10.1038/jid.2013.23. Epub 2013 Jan 21. J Invest Dermatol. 2013. PMID: 23337888 Free article.

2

Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression.

Woodcock SA, Rushton HJ, Castañeda-Saucedo E, Myant K, White GR, Blyth K, Sansom OJ, Malliri A. Woodcock SA, et al. Curr Biol. 2010 Apr 13;20(7):669-75. doi: 10.1016/j.cub.2010.02.033. Epub 2010 Mar 25. Curr Biol. 2010. PMID: 20346677 Free PMC article.

3

Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation.

Whalley HJ, Porter AP, Diamantopoulou Z, White GR, Castañeda-Saucedo E, Malliri A. Whalley HJ, et al. Nat Commun. 2015 Jun 16;6:7437. doi: 10.1038/ncomms8437. Nat Commun. 2015. PMID: 26078008 Free PMC article.

4

The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly.

Rooney C, White G, Nazgiewicz A, Woodcock SA, Anderson KI, Ballestrem C, Malliri A. Rooney C, et al. Among authors: white g. EMBO Rep. 2010 Apr;11(4):292-8. doi: 10.1038/embor.2010.10. Epub 2010 Mar 12. EMBO Rep. 2010. PMID: 20224579 Free PMC article.

5

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration.

Marei H, Carpy A, Woroniuk A, Vennin C, White G, Timpson P, Macek B, Malliri A. Marei H, et al. Among authors: white g. Nat Commun. 2016 Feb 18;7:10664. doi: 10.1038/ncomms10664. Nat Commun. 2016. PMID: 26887924 Free PMC article.

6

TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells.

Diamantopoulou Z, White G, Fadlullah MZH, Dreger M, Pickering K, Maltas J, Ashton G, MacLeod R, Baillie GS, Kouskoff V, Lacaud G, Murray GI, Sansom OJ, Hurlstone AFL, Malliri A. Diamantopoulou Z, et al. Among authors: white g. Cancer Cell. 2017 May 8;31(5):621-634.e6. doi: 10.1016/j.ccell.2017.03.007. Epub 2017 Apr 13. Cancer Cell. 2017. PMID: 28416184 Free PMC article.

7

TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change.

Payapilly A, Guilbert R, Descamps T, White G, Magee P, Zhou C, Kerr A, Simpson KL, Blackhall F, Dive C, Malliri A. Payapilly A, et al. Among authors: white g. Cell Rep. 2021 Nov 9;37(6):109979. doi: 10.1016/j.celrep.2021.109979. Cell Rep. 2021. PMID: 34758330 Free PMC article.

8

STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap.

Woroniuk A, Porter A, White G, Newman DT, Diamantopoulou Z, Waring T, Rooney C, Strathdee D, Marston DJ, Hahn KM, Sansom OJ, Zech T, Malliri A. Woroniuk A, et al. Among authors: white g. Nat Commun. 2018 May 29;9(1):2124. doi: 10.1038/s41467-018-04404-4. Nat Commun. 2018. PMID: 29844364 Free PMC article.

9

The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia.

Porter AP, White GRM, Mack NA, Malliri A. Porter AP, et al. J Cell Sci. 2019 Jul 15;132(14):jcs230086. doi: 10.1242/jcs.230086. J Cell Sci. 2019. PMID: 31289196 Free PMC article.

10

The RAC1 activator Tiam1 regulates centriole duplication through controlling PLK4 levels.

Porter AP, Reed H, White GRM, Ogg EL, Whalley HJ, Malliri A. Porter AP, et al. J Cell Sci. 2021 Apr 1;134(7):jcs252502. doi: 10.1242/jcs.252502. Epub 2021 Apr 13. J Cell Sci. 2021. PMID: 33758078 Free PMC article.

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