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Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation.
Gandhirajan RK, Meng S, Chandramoorthy HC, Mallilankaraman K, Mancarella S, Gao H, Razmpour R, Yang XF, Houser SR, Chen J, Koch WJ, Wang H, Soboloff J, Gill DL, Madesh M. Gandhirajan RK, et al. Among authors: wang h. J Clin Invest. 2013 Feb;123(2):887-902. doi: 10.1172/JCI65647. Epub 2013 Jan 25. J Clin Invest. 2013. PMID: 23348743 Free PMC article.
Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle.
Mancarella S, Potireddy S, Wang Y, Gao H, Gandhirajan RK, Autieri M, Scalia R, Cheng Z, Wang H, Madesh M, Houser SR, Gill DL. Mancarella S, et al. Among authors: wang h, wang y. FASEB J. 2013 Mar;27(3):893-906. doi: 10.1096/fj.12-215293. Epub 2012 Nov 16. FASEB J. 2013. PMID: 23159931 Free PMC article.
We conclude that STIM1-regulated Ca(2+) homeostasis is crucial for NFAT-mediated transcriptional control required for induction of SMC proliferation, development, and growth responses to injury.-Mancarella, S., Potireddy, S., Wang, Y., Gao, H., Gandhirajan, K., Auti …
We conclude that STIM1-regulated Ca(2+) homeostasis is crucial for NFAT-mediated transcriptional control required for induction of SMC proli …
Inflammasomes: sensors of metabolic stresses for vascular inflammation.
Yin Y, Pastrana JL, Li X, Huang X, Mallilankaraman K, Choi ET, Madesh M, Wang H, Yang XF. Yin Y, et al. Among authors: wang h. Front Biosci (Landmark Ed). 2013 Jan 1;18(2):638-49. doi: 10.2741/4127. Front Biosci (Landmark Ed). 2013. PMID: 23276949 Free PMC article. Review.
Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell Activation.
Li X, Fang P, Li Y, Kuo YM, Andrews AJ, Nanayakkara G, Johnson C, Fu H, Shan H, Du F, Hoffman NE, Yu D, Eguchi S, Madesh M, Koch WJ, Sun J, Jiang X, Wang H, Yang X. Li X, et al. Among authors: wang h. Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1090-100. doi: 10.1161/ATVBAHA.115.306964. Epub 2016 Apr 28. Arterioscler Thromb Vasc Biol. 2016. PMID: 27127201 Free PMC article.
149,443 results
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