Mahadevan D - Search Results

1

An integrin-targeted, pan-isoform, phosphoinositide-3 kinase inhibitor, SF1126, has activity against multiple myeloma in vivo.

De P, Dey N, Terakedis B, Bergsagel PL, Li ZH, Mahadevan D, Garlich JR, Trudel S, Makale MT, Durden DL. De P, et al. Among authors: mahadevan d. Cancer Chemother Pharmacol. 2013 Apr;71(4):867-81. doi: 10.1007/s00280-013-2078-0. Epub 2013 Jan 25. Cancer Chemother Pharmacol. 2013. PMID: 23355037 Free PMC article. Clinical Trial.

2

Phase I pharmacokinetic and pharmacodynamic study of the pan-PI3K/mTORC vascular targeted pro-drug SF1126 in patients with advanced solid tumours and B-cell malignancies.

Mahadevan D, Chiorean EG, Harris WB, Von Hoff DD, Stejskal-Barnett A, Qi W, Anthony SP, Younger AE, Rensvold DM, Cordova F, Shelton CF, Becker MD, Garlich JR, Durden DL, Ramanathan RK. Mahadevan D, et al. Eur J Cancer. 2012 Dec;48(18):3319-27. doi: 10.1016/j.ejca.2012.06.027. Epub 2012 Aug 23. Eur J Cancer. 2012. PMID: 22921184 Free PMC article. Clinical Trial.

3

AT9283, a novel aurora kinase inhibitor, suppresses tumor growth in aggressive B-cell lymphomas.

Qi W, Liu X, Cooke LS, Persky DO, Miller TP, Squires M, Mahadevan D. Qi W, et al. Among authors: mahadevan d. Int J Cancer. 2012 Jun 15;130(12):2997-3005. doi: 10.1002/ijc.26324. Epub 2011 Nov 19. Int J Cancer. 2012. PMID: 21796626

4

Phase I study of samalizumab in chronic lymphocytic leukemia and multiple myeloma: blockade of the immune checkpoint CD200.

Mahadevan D, Lanasa MC, Farber C, Pandey M, Whelden M, Faas SJ, Ulery T, Kukreja A, Li L, Bedrosian CL, Zhang X, Heffner LT. Mahadevan D, et al. J Immunother Cancer. 2019 Aug 23;7(1):227. doi: 10.1186/s40425-019-0710-1. J Immunother Cancer. 2019. PMID: 31443741 Free PMC article. Clinical Trial.

5

MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer.

Qi W, Cooke LS, Stejskal A, Riley C, Croce KD, Saldanha JW, Bearss D, Mahadevan D. Qi W, et al. Among authors: mahadevan d. BMC Cancer. 2009 May 11;9:142. doi: 10.1186/1471-2407-9-142. BMC Cancer. 2009. PMID: 19432987 Free PMC article.

6

Phase I single dose, two-period and two-sequence cross-over trial to evaluate the relative bioavailability of two oral pimasertib formulations in advanced cancer patients.

Mahadevan D, Mita M, Richards D, McClay E, Heist RS, Kumar A, Sundararajan S, Naing A. Mahadevan D, et al. Cancer Chemother Pharmacol. 2017 Apr;79(4):681-688. doi: 10.1007/s00280-017-3258-0. Epub 2017 Mar 13. Cancer Chemother Pharmacol. 2017. PMID: 28289865 Clinical Trial.

7

Novel targeted therapies and combinations for the treatment of multiple myeloma.

Agarwal A, Mahadevan D. Agarwal A, et al. Among authors: mahadevan d. Cardiovasc Hematol Disord Drug Targets. 2013 Mar 1;13(1):2-15. doi: 10.2174/1871529x11313010002. Cardiovasc Hematol Disord Drug Targets. 2013. PMID: 22882073 Review.

8

The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells.

Welsh JW, Mahadevan D, Ellsworth R, Cooke L, Bearss D, Stea B. Welsh JW, et al. Among authors: mahadevan d. Radiat Oncol. 2009 Dec 22;4:69. doi: 10.1186/1748-717X-4-69. Radiat Oncol. 2009. PMID: 20028557 Free PMC article.

9

A comprehensive review of protein kinase inhibitors for cancer therapy.

Kannaiyan R, Mahadevan D. Kannaiyan R, et al. Among authors: mahadevan d. Expert Rev Anticancer Ther. 2018 Dec;18(12):1249-1270. doi: 10.1080/14737140.2018.1527688. Epub 2018 Oct 9. Expert Rev Anticancer Ther. 2018. PMID: 30259761 Free PMC article. Review.

10

Phase II study of bi-weekly temozolomide plus bevacizumab for adult patients with recurrent glioblastoma.

Badruddoja MA, Pazzi M, Sanan A, Schroeder K, Kuzma K, Norton T, Scully T, Mahadevan D, Ahmadi MM. Badruddoja MA, et al. Among authors: mahadevan d. Cancer Chemother Pharmacol. 2017 Oct;80(4):715-721. doi: 10.1007/s00280-017-3405-7. Epub 2017 Aug 14. Cancer Chemother Pharmacol. 2017. PMID: 28808777 Clinical Trial.

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