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Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays.
Wetmore BA, Wambaugh JF, Ferguson SS, Li L, Clewell HJ 3rd, Judson RS, Freeman K, Bao W, Sochaski MA, Chu TM, Black MB, Healy E, Allen B, Andersen ME, Wolfinger RD, Thomas RS. Wetmore BA, et al. Among authors: andersen me. Toxicol Sci. 2013 Apr;132(2):327-46. doi: 10.1093/toxsci/kft012. Epub 2013 Jan 28. Toxicol Sci. 2013. PMID: 23358191
Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.
Rotroff DM, Wetmore BA, Dix DJ, Ferguson SS, Clewell HJ, Houck KA, Lecluyse EL, Andersen ME, Judson RS, Smith CM, Sochaski MA, Kavlock RJ, Boellmann F, Martin MT, Reif DM, Wambaugh JF, Thomas RS. Rotroff DM, et al. Among authors: andersen me. Toxicol Sci. 2010 Oct;117(2):348-58. doi: 10.1093/toxsci/kfq220. Epub 2010 Jul 16. Toxicol Sci. 2010. PMID: 20639261 Free PMC article.
455 results