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FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors.
Neumann M, Coskun E, Fransecky L, Mochmann LH, Bartram I, Sartangi NF, Heesch S, Gökbuget N, Schwartz S, Brandts C, Schlee C, Haas R, Dührsen U, Griesshammer M, Döhner H, Ehninger G, Burmeister T, Blau O, Thiel E, Hoelzer D, Hofmann WK, Baldus CD. Neumann M, et al. Among authors: hoelzer d. PLoS One. 2013;8(1):e53190. doi: 10.1371/journal.pone.0053190. Epub 2013 Jan 24. PLoS One. 2013. PMID: 23359050 Free PMC article.
Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia.
Heesch S, Goekbuget N, Stroux A, Tanchez JO, Schlee C, Burmeister T, Schwartz S, Blau O, Keilholz U, Busse A, Hoelzer D, Thiel E, Hofmann WK, Baldus CD. Heesch S, et al. Among authors: hoelzer d. Haematologica. 2010 Jun;95(6):942-9. doi: 10.3324/haematol.2009.016386. Epub 2010 Apr 30. Haematologica. 2010. PMID: 20435628 Free PMC article.
Expression of IGFBP7 in acute leukemia is regulated by DNA methylation.
Heesch S, Bartram I, Neumann M, Reins J, Mossner M, Schlee C, Stroux A, Haferlach T, Goekbuget N, Hoelzer D, Hofmann WK, Thiel E, Baldus CD. Heesch S, et al. Among authors: hoelzer d. Cancer Sci. 2011 Jan;102(1):253-9. doi: 10.1111/j.1349-7006.2010.01760.x. Epub 2010 Oct 29. Cancer Sci. 2011. PMID: 21040219 Free article.
Acute leukemias of ambiguous lineage in adults: molecular and clinical characterization.
Heesch S, Neumann M, Schwartz S, Bartram I, Schlee C, Burmeister T, Hänel M, Ganser A, Heuser M, Wendtner CM, Berdel WE, Gökbuget N, Hoelzer D, Hofmann WK, Thiel E, Baldus CD. Heesch S, et al. Among authors: hoelzer d. Ann Hematol. 2013 Jun;92(6):747-58. doi: 10.1007/s00277-013-1694-4. Epub 2013 Feb 15. Ann Hematol. 2013. PMID: 23412561
Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations.
Neumann M, Heesch S, Schlee C, Schwartz S, Gökbuget N, Hoelzer D, Konstandin NP, Ksienzyk B, Vosberg S, Graf A, Krebs S, Blum H, Raff T, Brüggemann M, Hofmann WK, Hecht J, Bohlander SK, Greif PA, Baldus CD. Neumann M, et al. Among authors: hoelzer d. Blood. 2013 Jun 6;121(23):4749-52. doi: 10.1182/blood-2012-11-465138. Epub 2013 Apr 19. Blood. 2013. PMID: 23603912 Free article.
Low expression of T-cell transcription factor BCL11b predicts inferior survival in adult standard risk T-cell acute lymphoblastic leukemia patients.
Bartram I, Gökbuget N, Schlee C, Heesch S, Fransecky L, Schwartz S, Stuhlmann R, Schäfer-Eckhart K, Starck M, Reichle A, Hoelzer D, Baldus CD, Neumann M. Bartram I, et al. Among authors: hoelzer d. J Hematol Oncol. 2014 Jul 15;7:51. doi: 10.1186/s13045-014-0051-y. J Hematol Oncol. 2014. PMID: 25023966 Free PMC article.
675 results