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146 results

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Page 1
Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells.
Sims AC, Tilton SC, Menachery VD, Gralinski LE, Schäfer A, Matzke MM, Webb-Robertson BJ, Chang J, Luna ML, Long CE, Shukla AK, Bankhead AR 3rd, Burkett SE, Zornetzer G, Tseng CT, Metz TO, Pickles R, McWeeney S, Smith RD, Katze MG, Waters KM, Baric RS. Sims AC, et al. Among authors: menachery vd. J Virol. 2013 Apr;87(7):3885-902. doi: 10.1128/JVI.02520-12. Epub 2013 Jan 30. J Virol. 2013. PMID: 23365422 Free PMC article.
Engineering SARS-CoV-2 cocktail antibodies into a bispecific format improves neutralizing potency and breadth.
Ku Z, Xie X, Lin J, Gao P, El Sahili A, Su H, Liu Y, Ye X, Li X, Fan X, Goh BC, Xiong W, Boyd H, Muruato AE, Deng H, Xia H, Jing Z, Kalveram BK, Menachery VD, Zhang N, Lescar J, Shi PY, An Z. Ku Z, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2022 Feb 1:2022.02.01.478504. doi: 10.1101/2022.02.01.478504. bioRxiv. 2022. Update in: Nat Commun. 2022 Sep 22;13(1):5552. doi: 10.1038/s41467-022-33284-y PMID: 35132410 Free PMC article. Updated. Preprint.
SARS-CoV-2 hijacks fragile X mental retardation proteins for efficient infection.
Garvanska DH, Alvarado RE, Mundt FO, Nilsson E, Duel JK, Coscia F, Lindqvist R, Lokugamage K, Johnson BA, Plante JA, Morris DR, Vu MN, Estes LK, McLeland AM, Walker J, Crocquet-Valdes PA, Mendez BL, Plante KS, Walker DH, Weisser MB, Overby AK, Mann M, Menachery VD, Nilsson J. Garvanska DH, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2023 Sep 1:2023.09.01.555899. doi: 10.1101/2023.09.01.555899. bioRxiv. 2023. PMID: 37693415 Free PMC article. Preprint.
Mouse Adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.
Muruato A, Vu MN, Johnson BA, Davis-Gardner ME, Vanderheiden A, Lokugmage K, Schindewolf C, Crocquet-Valdes PA, Langsjoen RM, Plante JA, Plante KS, Weaver SC, Debbink K, Routh AL, Walker D, Suthar MS, Xie X, Shi PY, Xie X, Menachery VD. Muruato A, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2021 May 4:2021.05.03.442357. doi: 10.1101/2021.05.03.442357. bioRxiv. 2021. Update in: PLoS Biol. 2021 Nov 4;19(11):e3001284. doi: 10.1371/journal.pbio.3001284 PMID: 33972939 Free PMC article. Updated. Preprint.
The N501Y spike substitution enhances SARS-CoV-2 transmission.
Liu Y, Liu J, Plante KS, Plante JA, Xie X, Zhang X, Ku Z, An Z, Scharton D, Schindewolf C, Menachery VD, Shi PY, Weaver SC. Liu Y, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2021 Mar 9:2021.03.08.434499. doi: 10.1101/2021.03.08.434499. bioRxiv. 2021. Update in: Nature. 2022 Feb;602(7896):294-299. doi: 10.1038/s41586-021-04245-0 PMID: 33758836 Free PMC article. Updated. Preprint.
Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection.
Vu MN, Alvarado RE, Morris DR, Lokugamage KG, Zhou Y, Morgan AL, Estes LK, McLeland AM, Schindewolf C, Plante JA, Ahearn YP, Meyers WM, Murray JT, Crocquet-Valdes PA, Weaver SC, Walker DH, Russell WK, Routh AL, Plante KS, Menachery V. Vu MN, et al. bioRxiv [Preprint]. 2023 Jul 10:2023.04.17.536926. doi: 10.1101/2023.04.17.536926. bioRxiv. 2023. PMID: 37131784 Free PMC article. Preprint.
Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis.
Johnson BA, Zhou Y, Lokugamage KG, Vu MN, Bopp N, Crocquet-Valdes PA, Kalveram B, Schindewolf C, Liu Y, Scharton D, Plante JA, Xie X, Aguilar P, Weaver SC, Shi PY, Walker DH, Routh AL, Plante KS, Menachery VD. Johnson BA, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2022 Mar 28:2021.10.14.464390. doi: 10.1101/2021.10.14.464390. bioRxiv. 2022. Update in: PLoS Pathog. 2022 Jun 21;18(6):e1010627. doi: 10.1371/journal.ppat.1010627 PMID: 34671771 Free PMC article. Updated. Preprint.
Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant.
Liu Y, Liu J, Johnson BA, Xia H, Ku Z, Schindewolf C, Widen SG, An Z, Weaver SC, Menachery VD, Xie X, Shi PY. Liu Y, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2021 Sep 5:2021.08.12.456173. doi: 10.1101/2021.08.12.456173. bioRxiv. 2021. Update in: Cell Rep. 2022 May 17;39(7):110829. doi: 10.1016/j.celrep.2022.110829 PMID: 34462752 Free PMC article. Updated. Preprint.
Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLpro.
Hou N, Shuai L, Zhang L, Xie X, Tang K, Zhu Y, Yu Y, Zhang W, Tan Q, Zhong G, Wen Z, Wang C, He X, Huo H, Gao H, Xu Y, Xue J, Peng C, Zou J, Schindewolf C, Menachery V, Su W, Yuan Y, Shen Z, Zhang R, Yuan S, Yu H, Shi PY, Bu Z, Huang J, Hu Q. Hou N, et al. ACS Cent Sci. 2023 Jan 25;9(2):217-227. doi: 10.1021/acscentsci.2c01359. eCollection 2023 Feb 22. ACS Cent Sci. 2023. PMID: 36844503 Free PMC article.
CCR2-dependent monocyte-derived cells restrict SARS-CoV-2 infection.
Vanderheiden A, Thomas J, Soung AL, Davis-Gardner ME, Floyd K, Jin F, Cowan DA, Pellegrini K, Creanga A, Pegu A, Derrien-Colemyn A, Shi PY, Grakoui A, Klein RS, Bosinger SE, Kohlmeier JE, Menachery VD, Suthar MS. Vanderheiden A, et al. Among authors: menachery vd. bioRxiv [Preprint]. 2021 May 4:2021.05.03.442538. doi: 10.1101/2021.05.03.442538. bioRxiv. 2021. Update in: mBio. 2021 Dec 21;12(6):e0274921. doi: 10.1128/mBio.02749-21 PMID: 33972938 Free PMC article. Updated. Preprint.
146 results