Singh RR - Search Results

1

Functional inhibition of BCL2 is needed to increase the susceptibility to apoptosis to SMO inhibitors in diffuse large B-cell lymphoma of germinal center subtype.

Kunkalla K, Liu Y, Qu C, Leventaki V, Agarwal NK, Singh RR, Vega F. Kunkalla K, et al. Among authors: singh rr. Ann Hematol. 2013 Jun;92(6):777-87. doi: 10.1007/s00277-013-1684-6. Epub 2013 Feb 1. Ann Hematol. 2013. PMID: 23370596 Free PMC article.

2

ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma.

Singh RR, Kunkalla K, Qu C, Schlette E, Neelapu SS, Samaniego F, Vega F. Singh RR, et al. Oncogene. 2011 Dec 8;30(49):4874-86. doi: 10.1038/onc.2011.195. Epub 2011 May 30. Oncogene. 2011. PMID: 21625222 Free PMC article.

3

Defining causative factors contributing in the activation of hedgehog signaling in diffuse large B-cell lymphoma.

Ramirez E, Singh RR, Kunkalla K, Liu Y, Qu C, Cain C, Multani AS, Lennon PA, Jackacky J, Ho M, Dawud S, Gu J, Yang S, Hu PC, Vega F. Ramirez E, et al. Among authors: singh rr. Leuk Res. 2012 Oct;36(10):1267-73. doi: 10.1016/j.leukres.2012.06.014. Epub 2012 Jul 17. Leuk Res. 2012. PMID: 22809693 Free PMC article.

4

Trimeric G protein-CARMA1 axis links smoothened, the hedgehog receptor transducer, to NF-κB activation in diffuse large B-cell lymphoma.

Qu C, Liu Y, Kunkalla K, Singh RR, Blonska M, Lin X, Agarwal NK, Vega F. Qu C, et al. Among authors: singh rr. Blood. 2013 Jun 6;121(23):4718-28. doi: 10.1182/blood-2012-12-470153. Epub 2013 Apr 30. Blood. 2013. PMID: 23632891 Free PMC article.

5

Hedgehog signaling pathway is activated in diffuse large B-cell lymphoma and contributes to tumor cell survival and proliferation.

Singh RR, Kim JE, Davuluri Y, Drakos E, Cho-Vega JH, Amin HM, Vega F. Singh RR, et al. Leukemia. 2010 May;24(5):1025-36. doi: 10.1038/leu.2010.35. Epub 2010 Mar 4. Leukemia. 2010. PMID: 20200556

6

Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21).

Drakos E, Singh RR, Rassidakis GZ, Schlette E, Li J, Claret FX, Ford RJ Jr, Vega F, Medeiros LJ. Drakos E, et al. Among authors: singh rr. Leukemia. 2011 May;25(5):856-67. doi: 10.1038/leu.2011.28. Epub 2011 Mar 11. Leukemia. 2011. PMID: 21394100 Free PMC article.

7

Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma.

Singh RR, Cho-Vega JH, Davuluri Y, Ma S, Kasbidi F, Milito C, Lennon PA, Drakos E, Medeiros LJ, Luthra R, Vega F. Singh RR, et al. Cancer Res. 2009 Mar 15;69(6):2550-8. doi: 10.1158/0008-5472.CAN-08-1808. Epub 2009 Feb 24. Cancer Res. 2009. PMID: 19244133

8

Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma.

Kim JE, Singh RR, Cho-Vega JH, Drakos E, Davuluri Y, Khokhar FA, Fayad L, Medeiros LJ, Vega F. Kim JE, et al. Among authors: singh rr. Mod Pathol. 2009 Oct;22(10):1312-20. doi: 10.1038/modpathol.2009.98. Epub 2009 Jul 10. Mod Pathol. 2009. PMID: 19593328 Free article.

9

Glioma-associated oncogene homologue 3, a hedgehog transcription factor, is highly expressed in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma.

Greaves WO, Kim JE, Singh RR, Drakos E, Kunkalla K, Sánchez-Espiridión B, Garcia JF, Medeiros LJ, Vega F. Greaves WO, et al. Among authors: singh rr. Hum Pathol. 2011 Nov;42(11):1643-52. doi: 10.1016/j.humpath.2010.12.023. Epub 2011 Apr 29. Hum Pathol. 2011. PMID: 21531006 Free PMC article.

10

Detection of ABCC1 expression in classical Hodgkin lymphoma is associated with increased risk of treatment failure using standard chemotherapy protocols.

Greaves W, Xiao L, Sanchez-Espiridion B, Kunkalla K, Dave KS, Liang CS, Singh RR, Younes A, Medeiros LJ, Vega F. Greaves W, et al. Among authors: singh rr. J Hematol Oncol. 2012 Aug 7;5:47. doi: 10.1186/1756-8722-5-47. J Hematol Oncol. 2012. PMID: 22871336 Free PMC article.

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