Yang D - Search Results

1

Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug.

Xiao D, Yang D, Guo L, Lu W, Charpentier M, Yan B. Xiao D, et al. Among authors: yang d. Br J Pharmacol. 2013 Apr;168(8):1989-99. doi: 10.1111/bph.12125. Br J Pharmacol. 2013. PMID: 23373735 Free PMC article.

2

Surge in expression of carboxylesterase 1 during the post-neonatal stage enables a rapid gain of the capacity to activate the anti-influenza prodrug oseltamivir.

Shi D, Yang D, Prinssen EP, Davies BE, Yan B. Shi D, et al. Among authors: yang d. J Infect Dis. 2011 Apr 1;203(7):937-42. doi: 10.1093/infdis/jiq145. J Infect Dis. 2011. PMID: 21402544 Free PMC article.

3

Scoparone potentiates transactivation of the bile salt export pump gene and this effect is enhanced by cytochrome P450 metabolism but abolished by a PKC inhibitor.

Yang D, Yang J, Shi D, Deng R, Yan B. Yang D, et al. Among authors: yang j. Br J Pharmacol. 2011 Nov;164(5):1547-57. doi: 10.1111/j.1476-5381.2011.01522.x. Br J Pharmacol. 2011. PMID: 21649640 Free PMC article.

4

Xiao D, Chen YT, Yang D, Yan B. Xiao D, et al. Among authors: yang d. Biochem Pharmacol. 2012 Jul 15;84(2):232-9. doi: 10.1016/j.bcp.2012.04.002. Epub 2012 Apr 10. Biochem Pharmacol. 2012. PMID: 22513142 Free PMC article.

5

Antioxidant sulforaphane and sensitizer trinitrobenzene sulfonate induce carboxylesterase-1 through a novel element transactivated by nuclear factor-E2 related factor-2.

Chen YT, Shi D, Yang D, Yan B. Chen YT, et al. Among authors: yang d. Biochem Pharmacol. 2012 Sep 15;84(6):864-71. doi: 10.1016/j.bcp.2012.06.025. Epub 2012 Jul 6. Biochem Pharmacol. 2012. PMID: 22776248 Free PMC article.

6

Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs.

Xiao D, Shi D, Yang D, Barthel B, Koch TH, Yan B. Xiao D, et al. Among authors: yang d. Biochem Pharmacol. 2013 Feb 1;85(3):439-47. doi: 10.1016/j.bcp.2012.11.026. Epub 2012 Dec 7. Biochem Pharmacol. 2013. PMID: 23228697 Free PMC article.

7

Mouse liver and kidney carboxylesterase (M-LK) rapidly hydrolyzes antitumor prodrug irinotecan and the N-terminal three quarter sequence determines substrate selectivity.

Xie M, Yang D, Wu M, Xue B, Yan B. Xie M, et al. Among authors: yang d. Drug Metab Dispos. 2003 Jan;31(1):21-7. doi: 10.1124/dmd.31.1.21. Drug Metab Dispos. 2003. PMID: 12485949

8

Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor.

Deng R, Yang D, Yang J, Yan B. Deng R, et al. Among authors: yang d, yang j. J Pharmacol Exp Ther. 2006 Apr;317(1):317-25. doi: 10.1124/jpet.105.097758. Epub 2005 Dec 21. J Pharmacol Exp Ther. 2006. PMID: 16371446 Free PMC article.

9

Antiplatelet agents aspirin and clopidogrel are hydrolyzed by distinct carboxylesterases, and clopidogrel is transesterificated in the presence of ethyl alcohol.

Tang M, Mukundan M, Yang J, Charpentier N, LeCluyse EL, Black C, Yang D, Shi D, Yan B. Tang M, et al. Among authors: yang d, yang j. J Pharmacol Exp Ther. 2006 Dec;319(3):1467-76. doi: 10.1124/jpet.106.110577. Epub 2006 Aug 30. J Pharmacol Exp Ther. 2006. PMID: 16943252

10

Anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel.

Shi D, Yang J, Yang D, LeCluyse EL, Black C, You L, Akhlaghi F, Yan B. Shi D, et al. Among authors: yang d, yang j. J Pharmacol Exp Ther. 2006 Dec;319(3):1477-84. doi: 10.1124/jpet.106.111807. Epub 2006 Sep 11. J Pharmacol Exp Ther. 2006. PMID: 16966469

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

24,173 results

Search Page

Filters