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Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury.
Arslan F, Lai RC, Smeets MB, Akeroyd L, Choo A, Aguor EN, Timmers L, van Rijen HV, Doevendans PA, Pasterkamp G, Lim SK, de Kleijn DP. Arslan F, et al. Among authors: van rijen hv. Stem Cell Res. 2013 May;10(3):301-12. doi: 10.1016/j.scr.2013.01.002. Epub 2013 Jan 14. Stem Cell Res. 2013. PMID: 23399448 Free article.
EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant.
van Empel VP, Bertrand AT, van Oort RJ, van der Nagel R, Engelen M, van Rijen HV, Doevendans PA, Crijns HJ, Ackerman SL, Sluiter W, De Windt LJ. van Empel VP, et al. Among authors: van rijen hv, van der nagel r, van oort rj. J Am Coll Cardiol. 2006 Aug 15;48(4):824-32. doi: 10.1016/j.jacc.2006.02.075. Epub 2006 Jul 25. J Am Coll Cardiol. 2006. PMID: 16904556 Free article.
Cardiomyocyte-restricted deletion of connexin43 during mouse development.
Eckardt D, Kirchhoff S, Kim JS, Degen J, Theis M, Ott T, Wiesmann F, Doevendans PA, Lamers WH, de Bakker JM, van Rijen HV, Schneider MD, Willecke K. Eckardt D, et al. Among authors: van rijen hv. J Mol Cell Cardiol. 2006 Dec;41(6):963-71. doi: 10.1016/j.yjmcc.2006.07.017. Epub 2006 Sep 11. J Mol Cell Cardiol. 2006. PMID: 16963078
Direct detection of myocardial fibrosis by MRI.
de Jong S, Zwanenburg JJ, Visser F, der Nagel Rv, van Rijen HV, Vos MA, de Bakker JM, Luijten PR. de Jong S, et al. Among authors: van rijen hv. J Mol Cell Cardiol. 2011 Dec;51(6):974-9. doi: 10.1016/j.yjmcc.2011.08.024. Epub 2011 Sep 1. J Mol Cell Cardiol. 2011. PMID: 21910997
Biomarkers of myocardial fibrosis.
de Jong S, van Veen TA, de Bakker JM, Vos MA, van Rijen HV. de Jong S, et al. Among authors: van rijen hv, van veen ta. J Cardiovasc Pharmacol. 2011 May;57(5):522-35. doi: 10.1097/FJC.0b013e31821823d9. J Cardiovasc Pharmacol. 2011. PMID: 21423029 Review.
Heterogeneous Connexin43 distribution in heart failure is associated with dispersed conduction and enhanced susceptibility to ventricular arrhythmias.
Boulaksil M, Winckels SK, Engelen MA, Stein M, van Veen TA, Jansen JA, Linnenbank AC, Bierhuizen MF, Groenewegen WA, van Oosterhout MF, Kirkels JH, de Jonge N, Varró A, Vos MA, de Bakker JM, van Rijen HV. Boulaksil M, et al. Among authors: van rijen hv, van oosterhout mf, van veen ta. Eur J Heart Fail. 2010 Sep;12(9):913-21. doi: 10.1093/eurjhf/hfq092. Epub 2010 Jun 9. Eur J Heart Fail. 2010. PMID: 20534605 Free article.
Calmodulin/CaMKII inhibition improves intercellular communication and impulse propagation in the heart and is antiarrhythmic under conditions when fibrosis is absent.
Takanari H, Bourgonje VJ, Fontes MS, Raaijmakers AJ, Driessen H, Jansen JA, van der Nagel R, Kok B, van Stuijvenberg L, Boulaksil M, Takemoto Y, Yamazaki M, Tsuji Y, Honjo H, Kamiya K, Kodama I, Anderson ME, van der Heyden MA, van Rijen HV, van Veen TA, Vos MA. Takanari H, et al. Among authors: van rijen hv. Cardiovasc Res. 2016 Sep;111(4):410-21. doi: 10.1093/cvr/cvw173. Epub 2016 Jun 29. Cardiovasc Res. 2016. PMID: 27357638 Free PMC article.
Arrhythmogenic Remodeling in Murine Models of Deoxycorticosterone Acetate-Salt-Induced and 5/6-Subtotal Nephrectomy-Salt-Induced Cardiorenal Disease.
Fontes MS, Papazova DA, van Koppen A, de Jong S, Korte SM, Bongartz LG, Nguyen TQ, Bierhuizen MF, de Boer TP, van Veen TA, Verhaar MC, Joles JA, van Rijen HV. Fontes MS, et al. Among authors: van rijen hv, van koppen a, van veen ta. Cardiorenal Med. 2015 Jun;5(3):208-18. doi: 10.1159/000430475. Epub 2015 Jun 5. Cardiorenal Med. 2015. PMID: 26195973 Free PMC article.
80 results