Kotzbauer PT - Search Results

1

Binding of the radioligand SIL23 to α-synuclein fibrils in Parkinson disease brain tissue establishes feasibility and screening approaches for developing a Parkinson disease imaging agent.

Bagchi DP, Yu L, Perlmutter JS, Xu J, Mach RH, Tu Z, Kotzbauer PT. Bagchi DP, et al. Among authors: kotzbauer pt. PLoS One. 2013;8(2):e55031. doi: 10.1371/journal.pone.0055031. Epub 2013 Feb 6. PLoS One. 2013. PMID: 23405108 Free PMC article.

2

Synthesis and in vitro evaluation of α-synuclein ligands.

Yu L, Cui J, Padakanti PK, Engel L, Bagchi DP, Kotzbauer PT, Tu Z. Yu L, et al. Among authors: kotzbauer pt. Bioorg Med Chem. 2012 Aug 1;20(15):4625-34. doi: 10.1016/j.bmc.2012.06.023. Epub 2012 Jun 19. Bioorg Med Chem. 2012. PMID: 22789706 Free PMC article.

3

Pathologic accumulation of α-synuclein and Aβ in Parkinson disease patients with dementia.

Kotzbauer PT, Cairns NJ, Campbell MC, Willis AW, Racette BA, Tabbal SD, Perlmutter JS. Kotzbauer PT, et al. Arch Neurol. 2012 Oct;69(10):1326-31. doi: 10.1001/archneurol.2012.1608. Arch Neurol. 2012. PMID: 22825369 Free PMC article.

4

Increased risk of parkinsonism associated with welding exposure.

Racette BA, Criswell SR, Lundin JI, Hobson A, Seixas N, Kotzbauer PT, Evanoff BA, Perlmutter JS, Zhang J, Sheppard L, Checkoway H. Racette BA, et al. Among authors: kotzbauer pt. Neurotoxicology. 2012 Oct;33(5):1356-61. doi: 10.1016/j.neuro.2012.08.011. Epub 2012 Sep 3. Neurotoxicology. 2012. PMID: 22975422 Free PMC article.

5

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds.

Holmes BB, DeVos SL, Kfoury N, Li M, Jacks R, Yanamandra K, Ouidja MO, Brodsky FM, Marasa J, Bagchi DP, Kotzbauer PT, Miller TM, Papy-Garcia D, Diamond MI. Holmes BB, et al. Among authors: kotzbauer pt. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):E3138-47. doi: 10.1073/pnas.1301440110. Epub 2013 Jul 29. Proc Natl Acad Sci U S A. 2013. PMID: 23898162 Free PMC article.

6

A quantitative study of α-synuclein pathology in fifteen cases of dementia associated with Parkinson disease.

Armstrong RA, Kotzbauer PT, Perlmutter JS, Campbell MC, Hurth KM, Schmidt RE, Cairns NJ. Armstrong RA, et al. Among authors: kotzbauer pt. J Neural Transm (Vienna). 2014 Feb;121(2):171-81. doi: 10.1007/s00702-013-1084-z. Epub 2013 Aug 31. J Neural Transm (Vienna). 2014. PMID: 23996276 Free PMC article.

7

Correlation between decreased CSF α-synuclein and Aβ₁₋₄₂ in Parkinson disease.

Buddhala C, Campbell MC, Perlmutter JS, Kotzbauer PT. Buddhala C, et al. Among authors: kotzbauer pt. Neurobiol Aging. 2015 Jan;36(1):476-84. doi: 10.1016/j.neurobiolaging.2014.07.043. Epub 2014 Aug 4. Neurobiol Aging. 2015. PMID: 25212463 Free PMC article.

8

Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein.

Zhang X, Jin H, Padakanti PK, Li J, Yang H, Fan J, Mach RH, Kotzbauer P, Tu Z. Zhang X, et al. Appl Sci (Basel). 2014 Mar 17;4(1):66-78. doi: 10.3390/app4010066. Appl Sci (Basel). 2014. PMID: 25642331 Free PMC article.

9

CSF proteins and resting-state functional connectivity in Parkinson disease.

Campbell MC, Koller JM, Snyder AZ, Buddhala C, Kotzbauer PT, Perlmutter JS. Campbell MC, et al. Among authors: kotzbauer pt. Neurology. 2015 Jun 16;84(24):2413-21. doi: 10.1212/WNL.0000000000001681. Epub 2015 May 15. Neurology. 2015. PMID: 25979701 Free PMC article.

10

Design, Synthesis, and Characterization of 3-(Benzylidene)indolin-2-one Derivatives as Ligands for α-Synuclein Fibrils.

Chu W, Zhou D, Gaba V, Liu J, Li S, Peng X, Xu J, Dhavale D, Bagchi DP, d'Avignon A, Shakerdge NB, Bacskai BJ, Tu Z, Kotzbauer PT, Mach RH. Chu W, et al. Among authors: kotzbauer pt. J Med Chem. 2015 Aug 13;58(15):6002-17. doi: 10.1021/acs.jmedchem.5b00571. Epub 2015 Jul 31. J Med Chem. 2015. PMID: 26177091 Free PMC article.

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