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27 results

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Page 1
Snx3 regulates recycling of the transferrin receptor and iron assimilation.
Chen C, Garcia-Santos D, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Shah DI, Cooney JD, Chen W, King MJ, Yien YY, Schultz IJ, Anderson H, Dalton AJ, Freedman ML, Kingsley PD, Palis J, Hattangadi SM, Lodish HF, Ward DM, Kaplan J, Maeda T, Ponka P, Paw BH. Chen C, et al. Among authors: yien yy. Cell Metab. 2013 Mar 5;17(3):343-52. doi: 10.1016/j.cmet.2013.01.013. Epub 2013 Feb 14. Cell Metab. 2013. PMID: 23416069 Free PMC article.
Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4.
Hildick-Smith GJ, Cooney JD, Garone C, Kremer LS, Haack TB, Thon JN, Miyata N, Lieber DS, Calvo SE, Akman HO, Yien YY, Huston NC, Branco DS, Shah DI, Freedman ML, Koehler CM, Italiano JE Jr, Merkenschlager A, Beblo S, Strom TM, Meitinger T, Freisinger P, Donati MA, Prokisch H, Mootha VK, DiMauro S, Paw BH. Hildick-Smith GJ, et al. Among authors: yien yy. Am J Hum Genet. 2013 Nov 7;93(5):906-14. doi: 10.1016/j.ajhg.2013.09.011. Epub 2013 Oct 10. Am J Hum Genet. 2013. PMID: 24119684 Free PMC article.
The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability.
Chung J, Bauer DE, Ghamari A, Nizzi CP, Deck KM, Kingsley PD, Yien YY, Huston NC, Chen C, Schultz IJ, Dalton AJ, Wittig JG, Palis J, Orkin SH, Lodish HF, Eisenstein RS, Cantor AB, Paw BH. Chung J, et al. Among authors: yien yy. Sci Signal. 2015 Apr 14;8(372):ra34. doi: 10.1126/scisignal.aaa5903. Sci Signal. 2015. PMID: 25872869 Free PMC article.
A role for iron deficiency in dopaminergic neurodegeneration.
Yien YY, Paw BH. Yien YY, et al. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3417-8. doi: 10.1073/pnas.1601976113. Epub 2016 Mar 16. Proc Natl Acad Sci U S A. 2016. PMID: 26984501 Free PMC article. No abstract available.
FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity.
Yien YY, Shi J, Chen C, Cheung JTM, Grillo AS, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King MJ, Ablain J, Li H, Zon LI, Palis J, Burke MD, Bauer DE, Orkin SH, Koehler CM, Phillips JD, Kaplan J, Ward DM, Lodish HF, Paw BH. Yien YY, et al. J Biol Chem. 2018 Dec 21;293(51):19797-19811. doi: 10.1074/jbc.RA118.002742. Epub 2018 Oct 26. J Biol Chem. 2018. PMID: 30366982 Free PMC article.
Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes.
Seguin A, Takahashi-Makise N, Yien YY, Huston NC, Whitman JC, Musso G, Wallace JA, Bradley T, Bergonia HA, Kafina MD, Matsumoto M, Igarashi K, Phillips JD, Paw BH, Kaplan J, Ward DM. Seguin A, et al. Among authors: yien yy. J Biol Chem. 2017 Sep 29;292(39):16284-16299. doi: 10.1074/jbc.M117.797415. Epub 2017 Aug 14. J Biol Chem. 2017. PMID: 28808058 Free PMC article.
TMEM14C is required for erythroid mitochondrial heme metabolism.
Yien YY, Robledo RF, Schultz IJ, Takahashi-Makise N, Gwynn B, Bauer DE, Dass A, Yi G, Li L, Hildick-Smith GJ, Cooney JD, Pierce EL, Mohler K, Dailey TA, Miyata N, Kingsley PD, Garone C, Hattangadi SM, Huang H, Chen W, Keenan EM, Shah DI, Schlaeger TM, DiMauro S, Orkin SH, Cantor AB, Palis J, Koehler CM, Lodish HF, Kaplan J, Ward DM, Dailey HA, Phillips JD, Peters LL, Paw BH. Yien YY, et al. J Clin Invest. 2014 Oct;124(10):4294-304. doi: 10.1172/JCI76979. Epub 2014 Aug 26. J Clin Invest. 2014. PMID: 25157825 Free PMC article.
27 results