Ding C - Search Results

1

Fragment-based drug design and identification of HJC0123, a novel orally bioavailable STAT3 inhibitor for cancer therapy.

Chen H, Yang Z, Ding C, Chu L, Zhang Y, Terry K, Liu H, Shen Q, Zhou J. Chen H, et al. Among authors: ding c. Eur J Med Chem. 2013 Apr;62:498-507. doi: 10.1016/j.ejmech.2013.01.023. Epub 2013 Jan 26. Eur J Med Chem. 2013. PMID: 23416191 Free PMC article.

2

Exploration of synthetic approaches and pharmacological evaluation of PNU-69176E and its stereoisomer as 5-HT2C receptor allosteric modulators.

Ding C, Bremer NM, Smith TD, Seitz PK, Anastasio NC, Cunningham KA, Zhou J. Ding C, et al. ACS Chem Neurosci. 2012 Jul 18;3(7):538-45. doi: 10.1021/cn300020x. Epub 2012 Apr 19. ACS Chem Neurosci. 2012. PMID: 22860223 Free PMC article.

3

A combined bioinformatics and chemoinformatics approach for developing asymmetric bivalent AMPA receptor positive allosteric modulators as neuroprotective agents.

Chen H, Wang CZ, Ding C, Wild C, Copits B, Swanson GT, Johnson KM, Zhou J. Chen H, et al. Among authors: ding c. ChemMedChem. 2013 Feb;8(2):226-30. doi: 10.1002/cmdc.201200554. Epub 2012 Dec 20. ChemMedChem. 2013. PMID: 23281122 Free PMC article.

4

Efficient Synthesis of ESI-09, A Novel Non-cyclic Nucleotide EPAC Antagonist.

Chen H, Ding C, Wild C, Liu H, Wang T, White MA, Cheng X, Zhou J. Chen H, et al. Among authors: ding c. Tetrahedron Lett. 2013 Mar 20;54(12):1546-1549. doi: 10.1016/j.tetlet.2013.01.024. Tetrahedron Lett. 2013. PMID: 23459418 Free PMC article.

5

Discovery of O-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents.

Chen H, Yang Z, Ding C, Chu L, Zhang Y, Terry K, Liu H, Shen Q, Zhou J. Chen H, et al. Among authors: ding c. ACS Med Chem Lett. 2013 Feb 14;4(2):180-185. doi: 10.1021/ml3003082. Epub 2013 Jan 15. ACS Med Chem Lett. 2013. PMID: 23459613 Free PMC article.

6

Novel nitrogen-enriched oridonin analogues with thiazole-fused A-ring: protecting group-free synthesis, enhanced anticancer profile, and improved aqueous solubility.

Ding C, Zhang Y, Chen H, Yang Z, Wild C, Chu L, Liu H, Shen Q, Zhou J. Ding C, et al. J Med Chem. 2013 Jun 27;56(12):5048-58. doi: 10.1021/jm400367n. Epub 2013 Jun 19. J Med Chem. 2013. PMID: 23746196 Free PMC article.

7

Overcoming synthetic challenges of oridonin A-ring structural diversification: regio- and stereoselective installation of azides and 1,2,3-triazoles at the C-1, C-2, or C-3 position.

Ding C, Zhang Y, Chen H, Wild C, Wang T, White MA, Shen Q, Zhou J. Ding C, et al. Org Lett. 2013 Jul 19;15(14):3718-21. doi: 10.1021/ol4015865. Epub 2013 Jul 8. Org Lett. 2013. PMID: 23834026 Free PMC article.

8

Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis.

Ding C, Zhang Y, Chen H, Yang Z, Wild C, Ye N, Ester CD, Xiong A, White MA, Shen Q, Zhou J. Ding C, et al. J Med Chem. 2013 Nov 14;56(21):8814-25. doi: 10.1021/jm401248x. Epub 2013 Oct 31. J Med Chem. 2013. PMID: 24128046 Free PMC article.

9

Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis.

Bohanon FJ, Wang X, Ding C, Ding Y, Radhakrishnan GL, Rastellini C, Zhou J, Radhakrishnan RS. Bohanon FJ, et al. Among authors: ding y, ding c. J Surg Res. 2014 Jul;190(1):55-63. doi: 10.1016/j.jss.2014.03.036. Epub 2014 Mar 20. J Surg Res. 2014. PMID: 24742622 Free PMC article.

10

Design, synthesis, and characterization of novel apigenin analogues that suppress pancreatic stellate cell proliferation in vitro and associated pancreatic fibrosis in vivo.

Chen H, Mrazek AA, Wang X, Ding C, Ding Y, Porro LJ, Liu H, Chao C, Hellmich MR, Zhou J. Chen H, et al. Among authors: ding y, ding c. Bioorg Med Chem. 2014 Jul 1;22(13):3393-404. doi: 10.1016/j.bmc.2014.04.043. Epub 2014 May 2. Bioorg Med Chem. 2014. PMID: 24837156 Free PMC article.

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