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Page 1
Significance of complete 1p/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution.
Boots-Sprenger SH, Sijben A, Rijntjes J, Tops BB, Idema AJ, Rivera AL, Bleeker FE, Gijtenbeek AM, Diefes K, Heathcock L, Aldape KD, Jeuken JW, Wesseling P. Boots-Sprenger SH, et al. Among authors: heathcock l. Mod Pathol. 2013 Jul;26(7):922-9. doi: 10.1038/modpathol.2012.166. Epub 2013 Feb 22. Mod Pathol. 2013. PMID: 23429602 Free article.
IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas.
Olar A, Wani KM, Alfaro-Munoz KD, Heathcock LE, van Thuijl HF, Gilbert MR, Armstrong TS, Sulman EP, Cahill DP, Vera-Bolanos E, Yuan Y, Reijneveld JC, Ylstra B, Wesseling P, Aldape KD. Olar A, et al. Among authors: heathcock le. Acta Neuropathol. 2015 Apr;129(4):585-96. doi: 10.1007/s00401-015-1398-z. Epub 2015 Feb 21. Acta Neuropathol. 2015. PMID: 25701198 Free PMC article.
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma.
Bhat KP, Salazar KL, Balasubramaniyan V, Wani K, Heathcock L, Hollingsworth F, James JD, Gumin J, Diefes KL, Kim SH, Turski A, Azodi Y, Yang Y, Doucette T, Colman H, Sulman EP, Lang FF, Rao G, Copray S, Vaillant BD, Aldape KD. Bhat KP, et al. Among authors: heathcock l. Genes Dev. 2011 Dec 15;25(24):2594-609. doi: 10.1101/gad.176800.111. Genes Dev. 2011. PMID: 22190458 Free PMC article.
DNA copy number analysis of Grade II-III and Grade IV gliomas reveals differences in molecular ontogeny including chromothripsis associated with IDH mutation status.
Cohen A, Sato M, Aldape K, Mason CC, Alfaro-Munoz K, Heathcock L, South ST, Abegglen LM, Schiffman JD, Colman H. Cohen A, et al. Among authors: heathcock l. Acta Neuropathol Commun. 2015 Jun 20;3:34. doi: 10.1186/s40478-015-0213-3. Acta Neuropathol Commun. 2015. PMID: 26091668 Free PMC article.
A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival.
Zheng S, Fu J, Vegesna R, Mao Y, Heathcock LE, Torres-Garcia W, Ezhilarasan R, Wang S, McKenna A, Chin L, Brennan CW, Yung WK, Weinstein JN, Aldape KD, Sulman EP, Chen K, Koul D, Verhaak RG. Zheng S, et al. Among authors: heathcock le. Genes Dev. 2013 Jul 1;27(13):1462-72. doi: 10.1101/gad.213686.113. Epub 2013 Jun 24. Genes Dev. 2013. PMID: 23796897 Free PMC article.
Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma.
Bhat KPL, Balasubramaniyan V, Vaillant B, Ezhilarasan R, Hummelink K, Hollingsworth F, Wani K, Heathcock L, James JD, Goodman LD, Conroy S, Long L, Lelic N, Wang S, Gumin J, Raj D, Kodama Y, Raghunathan A, Olar A, Joshi K, Pelloski CE, Heimberger A, Kim SH, Cahill DP, Rao G, Den Dunnen WFA, Boddeke HWGM, Phillips HS, Nakano I, Lang FF, Colman H, Sulman EP, Aldape K. Bhat KPL, et al. Among authors: heathcock l. Cancer Cell. 2013 Sep 9;24(3):331-46. doi: 10.1016/j.ccr.2013.08.001. Epub 2013 Aug 29. Cancer Cell. 2013. PMID: 23993863 Free PMC article.