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CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.
Lopez-Mejia IC, Lagarrigue S, Giralt A, Martinez-Carreres L, Martín J, Ortega S, Zanou N, Denechaud PD, Castillo-Armengol J, Chavey C, Orpinell M, Delacuisine B, Nasrallah A, Collodet C, Zhang L, Viollet B, Hardie DG, Fajas L. Lopez-Mejia IC, et al. Among authors: viollet b. Mol Cell. 2024 Jun 20;84(12):2397. doi: 10.1016/j.molcel.2024.05.021. Epub 2024 May 31. Mol Cell. 2024. PMID: 38823385 No abstract available.
The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions.
Lanfranchi M, Yandiev S, Meyer-Dilhet G, Ellouze S, Kerkhofs M, Dos Reis R, Garcia A, Blondet C, Amar A, Kneppers A, Polvèche H, Plassard D, Foretz M, Viollet B, Sakamoto K, Mounier R, Bourgeois CF, Raineteau O, Goillot E, Courchet J. Lanfranchi M, et al. Among authors: viollet b. Nat Commun. 2024 Mar 21;15(1):2487. doi: 10.1038/s41467-024-46146-6. Nat Commun. 2024. PMID: 38514619 Free PMC article.
The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells.
Claude-Taupin A, Isnard P, Bagattin A, Kuperwasser N, Roccio F, Ruscica B, Goudin N, Garfa-Traoré M, Regnier A, Turinsky L, Burtin M, Foretz M, Pontoglio M, Morel E, Viollet B, Terzi F, Codogno P, Dupont N. Claude-Taupin A, et al. Among authors: viollet b. Nat Commun. 2023 Dec 5;14(1):8056. doi: 10.1038/s41467-023-43775-1. Nat Commun. 2023. PMID: 38052799 Free PMC article.
Amino acid homeostasis is a target of metformin therapy.
Forteath C, Mordi I, Nisr R, Gutierrez-Lara EJ, Alqurashi N, Phair IR, Cameron AR, Beall C, Bahr I, Mohan M, Wong AKF, Dihoum A, Mohammad A, Palmer CNA, Lamont D, Sakamoto K, Viollet B, Foretz M, Lang CC, Rena G. Forteath C, et al. Among authors: viollet b. Mol Metab. 2023 Aug;74:101750. doi: 10.1016/j.molmet.2023.101750. Epub 2023 Jun 9. Mol Metab. 2023. PMID: 37302544 Free PMC article. Clinical Trial.
358 results