Larsen L - Search Results

1

Anti-leukemic activity of ubiquinone-based compounds targeting trans-plasma membrane electron transport.

Grasso C, Larsen L, McConnell M, Smith RA, Berridge MV. Grasso C, et al. Among authors: larsen l. J Med Chem. 2013 Apr 25;56(8):3168-76. doi: 10.1021/jm301585z. Epub 2013 Apr 10. J Med Chem. 2013. PMID: 23432053

2

Synthesis and anti-inflammatory structure-activity relationships of thiazine-quinoline-quinones: inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis.

Chia EW, Pearce AN, Berridge MV, Larsen L, Perry NB, Sansom CE, Godfrey CA, Hanton LR, Lu GL, Walton M, Denny WA, Webb VL, Copp BR, Harper JL. Chia EW, et al. Among authors: larsen l. Bioorg Med Chem. 2008 Nov 1;16(21):9432-42. doi: 10.1016/j.bmc.2008.09.052. Epub 2008 Sep 20. Bioorg Med Chem. 2008. PMID: 18835721

3

The novel phloroglucinol PMT7 kills glycolytic cancer cells by blocking autophagy and sensitizing to nutrient stress.

Broadley K, Larsen L, Herst PM, Smith RA, Berridge MV, McConnell MJ. Broadley K, et al. Among authors: larsen l. J Cell Biochem. 2011 Jul;112(7):1869-79. doi: 10.1002/jcb.23107. J Cell Biochem. 2011. PMID: 21433059

4

Incorporation of triphenylphosphonium functionality improves the inhibitory properties of phenothiazine derivatives in Mycobacterium tuberculosis.

Dunn EA, Roxburgh M, Larsen L, Smith RA, McLellan AD, Heikal A, Murphy MP, Cook GM. Dunn EA, et al. Among authors: larsen l. Bioorg Med Chem. 2014 Oct 1;22(19):5320-8. doi: 10.1016/j.bmc.2014.07.050. Epub 2014 Aug 7. Bioorg Med Chem. 2014. PMID: 25150092

5

An antiproliferative bis-prenylated quinone from the New Zealand brown alga Perithalia capillaris.

Sansom CE, Larsen L, Perry NB, Berridge MV, Chia EW, Harper JL, Webb VL. Sansom CE, et al. Among authors: larsen l. J Nat Prod. 2007 Dec;70(12):2042-4. doi: 10.1021/np070436t. Epub 2007 Dec 1. J Nat Prod. 2007. PMID: 18052030

6

Anti-inflammatory sesquiterpene-quinones from the New Zealand sponge Dysidea cf. cristagalli.

McNamara CE, Larsen L, Perry NB, Harper JL, Berridge MV, Chia EW, Kelly M, Webb VL. McNamara CE, et al. Among authors: larsen l. J Nat Prod. 2005 Sep;68(9):1431-3. doi: 10.1021/np050171n. J Nat Prod. 2005. PMID: 16180831

7

Anti-inflammatory thiazine alkaloids isolated from the New Zealand ascidian Aplidium sp.: inhibitors of the neutrophil respiratory burst in a model of gouty arthritis.

Pearce AN, Chia EW, Berridge MV, Clark GR, Harper JL, Larsen L, Maas EW, Page MJ, Perry NB, Webb VL, Copp BR. Pearce AN, et al. Among authors: larsen l. J Nat Prod. 2007 Jun;70(6):936-40. doi: 10.1021/np060626o. Epub 2007 May 11. J Nat Prod. 2007. PMID: 17497807

8

A mitochondria-targeted derivative of ascorbate: MitoC.

Finichiu PG, Larsen DS, Evans C, Larsen L, Bright TP, Robb EL, Trnka J, Prime TA, James AM, Smith RA, Murphy MP. Finichiu PG, et al. Among authors: larsen ds, larsen l. Free Radic Biol Med. 2015 Dec;89:668-78. doi: 10.1016/j.freeradbiomed.2015.07.160. Epub 2015 Oct 8. Free Radic Biol Med. 2015. PMID: 26453920 Free PMC article.

9

Mitochondrial accumulation of a lipophilic cation conjugated to an ionisable group depends on membrane potential, pH gradient and pK(a): implications for the design of mitochondrial probes and therapies.

Finichiu PG, James AM, Larsen L, Smith RA, Murphy MP. Finichiu PG, et al. Among authors: larsen l. J Bioenerg Biomembr. 2013 Feb;45(1-2):165-73. doi: 10.1007/s10863-012-9493-5. Epub 2012 Nov 22. J Bioenerg Biomembr. 2013. PMID: 23180142

10

Re-directing an alkylating agent to mitochondria alters drug target and cell death mechanism.

Mourtada R, Fonseca SB, Wisnovsky SP, Pereira MP, Wang X, Hurren R, Parfitt J, Larsen L, Smith RA, Murphy MP, Schimmer AD, Kelley SO. Mourtada R, et al. Among authors: larsen l. PLoS One. 2013 Apr 9;8(4):e60253. doi: 10.1371/journal.pone.0060253. Print 2013. PLoS One. 2013. PMID: 23585833 Free PMC article.

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