Stegmaier K - Search Results

1

Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer.

Roti G, Carlton A, Ross KN, Markstein M, Pajcini K, Su AH, Perrimon N, Pear WS, Kung AL, Blacklow SC, Aster JC, Stegmaier K. Roti G, et al. Among authors: stegmaier k. Cancer Cell. 2013 Mar 18;23(3):390-405. doi: 10.1016/j.ccr.2013.01.015. Epub 2013 Feb 21. Cancer Cell. 2013. PMID: 23434461 Free PMC article.

2

Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation.

Stegmaier K, Ross KN, Colavito SA, O'Malley S, Stockwell BR, Golub TR. Stegmaier K, et al. Nat Genet. 2004 Mar;36(3):257-63. doi: 10.1038/ng1305. Epub 2004 Feb 8. Nat Genet. 2004. PMID: 14770183

3

Gefitinib induces myeloid differentiation of acute myeloid leukemia.

Stegmaier K, Corsello SM, Ross KN, Wong JS, Deangelo DJ, Golub TR. Stegmaier K, et al. Blood. 2005 Oct 15;106(8):2841-8. doi: 10.1182/blood-2005-02-0488. Epub 2005 Jul 5. Blood. 2005. PMID: 15998836 Free PMC article.

4

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.

Hieronymus H, Lamb J, Ross KN, Peng XP, Clement C, Rodina A, Nieto M, Du J, Stegmaier K, Raj SM, Maloney KN, Clardy J, Hahn WC, Chiosis G, Golub TR. Hieronymus H, et al. Among authors: stegmaier k. Cancer Cell. 2006 Oct;10(4):321-30. doi: 10.1016/j.ccr.2006.09.005. Epub 2006 Sep 28. Cancer Cell. 2006. PMID: 17010675 Free article.

5

Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.

Stegmaier K, Wong JS, Ross KN, Chow KT, Peck D, Wright RD, Lessnick SL, Kung AL, Golub TR. Stegmaier K, et al. PLoS Med. 2007 Apr;4(4):e122. doi: 10.1371/journal.pmed.0040122. PLoS Med. 2007. PMID: 17425403 Free PMC article.

6

Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.

Hahn CK, Ross KN, Warrington IM, Mazitschek R, Kanegai CM, Wright RD, Kung AL, Golub TR, Stegmaier K. Hahn CK, et al. Among authors: stegmaier k. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9751-6. doi: 10.1073/pnas.0710413105. Epub 2008 Jul 7. Proc Natl Acad Sci U S A. 2008. PMID: 18607002 Free PMC article.

7

High-throughput gene expression profiling of memory differentiation in primary human T cells.

Haining WN, Angelosanto J, Brosnahan K, Ross K, Hahn C, Russell K, Drury L, Norton S, Nadler L, Stegmaier K. Haining WN, et al. Among authors: stegmaier k. BMC Immunol. 2008 Aug 1;9:44. doi: 10.1186/1471-2172-9-44. BMC Immunol. 2008. PMID: 18673556 Free PMC article.

8

Identification of AML1-ETO modulators by chemical genomics.

Corsello SM, Roti G, Ross KN, Chow KT, Galinsky I, DeAngelo DJ, Stone RM, Kung AL, Golub TR, Stegmaier K. Corsello SM, et al. Among authors: stegmaier k. Blood. 2009 Jun 11;113(24):6193-205. doi: 10.1182/blood-2008-07-166090. Epub 2009 Apr 17. Blood. 2009. PMID: 19377049 Free PMC article.

9

Proteomic and genetic approaches identify Syk as an AML target.

Hahn CK, Berchuck JE, Ross KN, Kakoza RM, Clauser K, Schinzel AC, Ross L, Galinsky I, Davis TN, Silver SJ, Root DE, Stone RM, DeAngelo DJ, Carroll M, Hahn WC, Carr SA, Golub TR, Kung AL, Stegmaier K. Hahn CK, et al. Among authors: stegmaier k. Cancer Cell. 2009 Oct 6;16(4):281-94. doi: 10.1016/j.ccr.2009.08.018. Cancer Cell. 2009. PMID: 19800574 Free PMC article.

10

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.

Aste-Amézaga M, Zhang N, Lineberger JE, Arnold BA, Toner TJ, Gu M, Huang L, Vitelli S, Vo KT, Haytko P, Zhao JZ, Baleydier F, L'Heureux S, Wang H, Gordon WR, Thoryk E, Andrawes MB, Tiyanont K, Stegmaier K, Roti G, Ross KN, Franlin LL, Wang H, Wang F, Chastain M, Bett AJ, Audoly LP, Aster JC, Blacklow SC, Huber HE. Aste-Amézaga M, et al. Among authors: stegmaier k. PLoS One. 2010 Feb 8;5(2):e9094. doi: 10.1371/journal.pone.0009094. PLoS One. 2010. PMID: 20161710 Free PMC article.

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