LeDuc B - Search Results

1

Effect of excipients on acetaminophen metabolism and its implications for prevention of liver injury.

Ganetsky M, Böhlke M, Pereira L, Williams D, LeDuc B, Guatam S, Salhanick SD. Ganetsky M, et al. Among authors: leduc b. J Clin Pharmacol. 2013 Apr;53(4):413-20. doi: 10.1002/jcph.24. Epub 2013 Feb 22. J Clin Pharmacol. 2013. PMID: 23436315 Free PMC article. Clinical Trial.

2

Determination of the kinetics of rat UDP-glucuronosyltransferases (UGTs) in liver and intestine using HPLC.

Narayanan R, LeDuc B, Williams DA. Narayanan R, et al. Among authors: leduc b. J Pharm Biomed Anal. 2000 Apr;22(3):527-40. doi: 10.1016/s0731-7085(00)00241-7. J Pharm Biomed Anal. 2000. PMID: 10766370

3

Effect of antipyrine coadministration on the kinetics of acetaminophen and lidocaine.

Blyden GT, Greenblatt DJ, LeDuc BW, Scavone JM. Blyden GT, et al. Among authors: leduc bw. Eur J Clin Pharmacol. 1988;35(4):413-7. doi: 10.1007/BF00561374. Eur J Clin Pharmacol. 1988. PMID: 3197750

4

Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol.

Chen M, LeDuc B, Kerr S, Howe D, Williams DA. Chen M, et al. Among authors: leduc b. Drug Metab Dispos. 2010 Mar;38(3):368-75. doi: 10.1124/dmd.109.029900. Epub 2009 Dec 11. Drug Metab Dispos. 2010. PMID: 20008037

5

Identification and characterization of two chloramphenicol glucuronides from the in vitro glucuronidation of chloramphenicol in human liver microsomes.

Chen M, Howe D, Leduc B, Kerr S, Williams DA. Chen M, et al. Among authors: leduc b. Xenobiotica. 2007 Sep;37(9):954-71. doi: 10.1080/00498250701620734. Xenobiotica. 2007. PMID: 17896323

6

In vitro metabolism of oxymetazoline: evidence for bioactivation to a reactive metabolite.

Mahajan MK, Uttamsingh V, Daniels JS, Gan LS, LeDuc BW, Williams DA. Mahajan MK, et al. Drug Metab Dispos. 2011 Apr;39(4):693-702. doi: 10.1124/dmd.110.036004. Epub 2010 Dec 21. Drug Metab Dispos. 2011. PMID: 21177487

7

Comparison of enzyme kinetics of warfarin analyzed by LC-MS/MS QTrap and differential mobility spectrometry.

Shaik AN, Grater R, Lulla M, Williams DA, Gan LL, Bohnert T, LeDuc BW. Shaik AN, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jan 1;1008:164-173. doi: 10.1016/j.jchromb.2015.11.036. Epub 2015 Nov 23. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 26655108

8

Mechanism of Drug-Drug Interactions Between Warfarin and Statins.

Shaik AN, Bohnert T, Williams DA, Gan LL, LeDuc BW. Shaik AN, et al. J Pharm Sci. 2016 Jun;105(6):1976-1986. doi: 10.1016/j.xphs.2016.03.011. Epub 2016 Apr 19. J Pharm Sci. 2016. PMID: 27103011

9

Glucuronidation of haloperidol by rat liver microsomes: involvement of family 2 UDP-glucuronosyltransferases.

Narayanan R, LeDuc B, Williams DA. Narayanan R, et al. Among authors: leduc b. Life Sci. 2004 Apr 2;74(20):2527-39. doi: 10.1016/j.lfs.2003.10.009. Life Sci. 2004. PMID: 15010263

10

Differential effect of cigarette smoking on antipyrine oxidation versus acetaminophen conjugation.

Scavone JM, Greenblatt DJ, LeDuc BW, Blyden GT, Luna BG, Harmatz JS. Scavone JM, et al. Among authors: leduc bw. Pharmacology. 1990;40(2):77-84. doi: 10.1159/000138644. Pharmacology. 1990. PMID: 2345775

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