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Dopamine D1 signaling organizes network dynamics underlying working memory.
Roffman JL, Tanner AS, Eryilmaz H, Rodriguez-Thompson A, Silverstein NJ, Ho NF, Nitenson AZ, Chonde DB, Greve DN, Abi-Dargham A, Buckner RL, Manoach DS, Rosen BR, Hooker JM, Catana C. Roffman JL, et al. Among authors: hooker jm. Sci Adv. 2016 Jun 3;2(6):e1501672. doi: 10.1126/sciadv.1501672. eCollection 2016 Jun. Sci Adv. 2016. PMID: 27386561 Free PMC article.
PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia.
Gilbert TM, Zürcher NR, Wu CJ, Bhanot A, Hightower BG, Kim M, Albrecht DS, Wey HY, Schroeder FA, Rodriguez-Thompson A, Morin TM, Hart KL, Pellegrini AM, Riley MM, Wang C, Stufflebeam SM, Haggarty SJ, Holt DJ, Loggia ML, Perlis RH, Brown HE, Roffman JL, Hooker JM. Gilbert TM, et al. Among authors: hooker jm. J Clin Invest. 2019 Jan 2;129(1):364-372. doi: 10.1172/JCI123743. Epub 2018 Dec 10. J Clin Invest. 2019. PMID: 30530989 Free PMC article. Clinical Trial.
The neuroinflammatory component of negative affect in patients with chronic pain.
Albrecht DS, Kim M, Akeju O, Torrado-Carvajal A, Edwards RR, Zhang Y, Bergan C, Protsenko E, Kucyi A, Wasan AD, Hooker JM, Napadow V, Loggia ML. Albrecht DS, et al. Among authors: hooker jm. Mol Psychiatry. 2021 Mar;26(3):864-874. doi: 10.1038/s41380-019-0433-1. Epub 2019 May 28. Mol Psychiatry. 2021. PMID: 31138890 Free PMC article.
Neuroepigenetic signatures of age and sex in the living human brain.
Gilbert TM, Zürcher NR, Catanese MC, Tseng CJ, Di Biase MA, Lyall AE, Hightower BG, Parmar AJ, Bhanot A, Wu CJ, Hibert ML, Kim M, Mahmood U, Stufflebeam SM, Schroeder FA, Wang C, Roffman JL, Holt DJ, Greve DN, Pasternak O, Kubicki M, Wey HY, Hooker JM. Gilbert TM, et al. Among authors: hooker jm. Nat Commun. 2019 Jul 3;10(1):2945. doi: 10.1038/s41467-019-11031-0. Nat Commun. 2019. PMID: 31270332 Free PMC article.
[11C]PBR28 MR-PET imaging reveals lower regional brain expression of translocator protein (TSPO) in young adult males with autism spectrum disorder.
Zürcher NR, Loggia ML, Mullett JE, Tseng C, Bhanot A, Richey L, Hightower BG, Wu C, Parmar AJ, Butterfield RI, Dubois JM, Chonde DB, Izquierdo-Garcia D, Wey HY, Catana C, Hadjikhani N, McDougle CJ, Hooker JM. Zürcher NR, et al. Among authors: hooker jm. Mol Psychiatry. 2021 May;26(5):1659-1669. doi: 10.1038/s41380-020-0682-z. Epub 2020 Feb 19. Mol Psychiatry. 2021. PMID: 32076115 Free PMC article.
In vivo human brain expression of histone deacetylases in bipolar disorder.
Tseng CJ, Gilbert TM, Catanese MC, Hightower BG, Peters AT, Parmar AJ, Kim M, Wang C, Roffman JL, Brown HE, Perlis RH, Zürcher NR, Hooker JM. Tseng CJ, et al. Among authors: hooker jm. Transl Psychiatry. 2020 Jul 8;10(1):224. doi: 10.1038/s41398-020-00911-5. Transl Psychiatry. 2020. PMID: 32641695 Free PMC article.
PET imaging demonstrates histone deacetylase target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in rat.
Schroeder FA, Wang C, Van de Bittner GC, Neelamegam R, Takakura WR, Karunakaran A, Wey HY, Reis SA, Gale J, Zhang YL, Holson EB, Haggarty SJ, Hooker JM. Schroeder FA, et al. Among authors: hooker jm. ACS Chem Neurosci. 2014 Oct 15;5(10):1055-62. doi: 10.1021/cn500162j. Epub 2014 Sep 19. ACS Chem Neurosci. 2014. PMID: 25188794 Free PMC article.
Preclinical PET Neuroimaging of [11C]Bexarotene.
Rotstein BH, Placzek MS, Krishnan HS, Pekošak A, Collier TL, Wang C, Liang SH, Burstein ES, Hooker JM, Vasdev N. Rotstein BH, et al. Among authors: hooker jm. Mol Imaging. 2016 Aug 23;15:1536012116663054. doi: 10.1177/1536012116663054. Print 2016. Mol Imaging. 2016. PMID: 27553293 Free PMC article.
222 results