Othman AA - Search Results

1

Azithromycin to prevent bronchopulmonary dysplasia in ureaplasma-infected preterm infants: pharmacokinetics, safety, microbial response, and clinical outcomes with a 20-milligram-per-kilogram single intravenous dose.

Viscardi RM, Othman AA, Hassan HE, Eddington ND, Abebe E, Terrin ML, Kaufman DA, Waites KB. Viscardi RM, et al. Among authors: othman aa. Antimicrob Agents Chemother. 2013 May;57(5):2127-33. doi: 10.1128/AAC.02183-12. Epub 2013 Feb 25. Antimicrob Agents Chemother. 2013. PMID: 23439637 Free PMC article. Clinical Trial.

2

Transport, metabolism, and in vivo population pharmacokinetics of the chloro benztropine analogs, a class of compounds extensively evaluated in animal models of drug abuse.

Othman AA, Syed SA, Newman AH, Eddington ND. Othman AA, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):344-53. doi: 10.1124/jpet.106.111245. Epub 2006 Sep 26. J Pharmacol Exp Ther. 2007. PMID: 17003230

3

Applicability of the dopamine and rate hypotheses in explaining the differences in behavioral pharmacology of the chloro-benztropine analogs: studies conducted using intracerebral microdialysis and population pharmacodynamic modeling.

Othman AA, Newman AH, Eddington ND. Othman AA, et al. J Pharmacol Exp Ther. 2007 Aug;322(2):760-9. doi: 10.1124/jpet.107.123315. Epub 2007 May 22. J Pharmacol Exp Ther. 2007. PMID: 17519385

4

Population pharmacokinetics of S(-)-carvedilol in healthy volunteers after administration of the immediate-release (IR) and the new controlled-release (CR) dosage forms of the racemate.

Othman AA, Tenero DM, Boyle DA, Eddington ND, Fossler MJ. Othman AA, et al. AAPS J. 2007 Jun 15;9(2):E208-18. doi: 10.1208/aapsj0902023. AAPS J. 2007. PMID: 17614362 Free PMC article. Clinical Trial.

5

Population pharmacokinetics, brain distribution, and pharmacodynamics of 2nd generation dopamine transporter selective benztropine analogs developed as potential substitute therapeutics for treatment of cocaine abuse.

Syed SA, Newman AH, Othman AA, Eddington ND. Syed SA, et al. Among authors: othman aa. J Pharm Sci. 2008 May;97(5):1993-2007. doi: 10.1002/jps.21123. J Pharm Sci. 2008. PMID: 17879975

6

The novel N-substituted benztropine analog GA2-50 possesses pharmacokinetic and pharmacodynamic profiles favorable for a candidate substitute medication for cocaine abuse.

Othman AA, Newman AH, Eddington ND. Othman AA, et al. J Pharm Sci. 2008 Dec;97(12):5453-70. doi: 10.1002/jps.21389. J Pharm Sci. 2008. PMID: 18425847 Free PMC article.

7

Evaluation of the transport, in vitro metabolism and pharmacokinetics of Salvinorin A, a potent hallucinogen.

Teksin ZS, Lee IJ, Nemieboka NN, Othman AA, Upreti VV, Hassan HE, Syed SS, Prisinzano TE, Eddington ND. Teksin ZS, et al. Among authors: othman aa. Eur J Pharm Biopharm. 2009 Jun;72(2):471-7. doi: 10.1016/j.ejpb.2009.01.002. Eur J Pharm Biopharm. 2009. PMID: 19462483 Free PMC article.

8

Pharmacokinetics, safety, and biologic effects of azithromycin in extremely preterm infants at risk for ureaplasma colonization and bronchopulmonary dysplasia.

Hassan HE, Othman AA, Eddington ND, Duffy L, Xiao L, Waites KB, Kaufman DA, Fairchild KD, Terrin ML, Viscardi RM. Hassan HE, et al. Among authors: othman aa. J Clin Pharmacol. 2011 Sep;51(9):1264-75. doi: 10.1177/0091270010382021. Epub 2010 Nov 23. J Clin Pharmacol. 2011. PMID: 21098694 Free PMC article.

9

Single- and multiple-dose pharmacokinetics, safety, and tolerability of the selective alpha7 neuronal nicotinic receptor agonist, ABT-107, in healthy human volunteers.

Othman AA, Lenz RA, Zhang J, Li J, Awni WM, Dutta S. Othman AA, et al. J Clin Pharmacol. 2011 Apr;51(4):512-26. doi: 10.1177/0091270010370460. Epub 2010 May 21. J Clin Pharmacol. 2011. PMID: 20495134 Clinical Trial.

10

The H3 antagonist ABT-288 is tolerated at significantly higher exposures in subjects with schizophrenia than in healthy volunteers.

Othman AA, Haig G, Florian H, Locke C, Gertsik L, Dutta S. Othman AA, et al. Br J Clin Pharmacol. 2014 Jun;77(6):965-74. doi: 10.1111/bcp.12281. Br J Clin Pharmacol. 2014. PMID: 24215171 Free PMC article. Clinical Trial.

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