De Weerd N - Search Results

1

Interferon-ε protects the female reproductive tract from viral and bacterial infection.

Fung KY, Mangan NE, Cumming H, Horvat JC, Mayall JR, Stifter SA, De Weerd N, Roisman LC, Rossjohn J, Robertson SA, Schjenken JE, Parker B, Gargett CE, Nguyen HP, Carr DJ, Hansbro PM, Hertzog PJ. Fung KY, et al. Among authors: de weerd n. Science. 2013 Mar 1;339(6123):1088-92. doi: 10.1126/science.1233321. Science. 2013. PMID: 23449591 Free PMC article.

2

Type I interferon receptors: biochemistry and biological functions.

de Weerd NA, Samarajiwa SA, Hertzog PJ. de Weerd NA, et al. J Biol Chem. 2007 Jul 13;282(28):20053-7. doi: 10.1074/jbc.R700006200. Epub 2007 May 14. J Biol Chem. 2007. PMID: 17502368 Free article. Review. No abstract available.

3

A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs.

Zhao W, Lee C, Piganis R, Plumlee C, de Weerd N, Hertzog PJ, Schindler C. Zhao W, et al. Among authors: de weerd n. J Immunol. 2008 Apr 15;180(8):5483-9. doi: 10.4049/jimmunol.180.8.5483. J Immunol. 2008. PMID: 18390731

4

Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2.

Piganis RA, De Weerd NA, Gould JA, Schindler CW, Mansell A, Nicholson SE, Hertzog PJ. Piganis RA, et al. J Biol Chem. 2011 Sep 30;286(39):33811-8. doi: 10.1074/jbc.M111.270207. Epub 2011 Jul 13. J Biol Chem. 2011. PMID: 21757742 Free PMC article.

5

Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape.

Bidwell BN, Slaney CY, Withana NP, Forster S, Cao Y, Loi S, Andrews D, Mikeska T, Mangan NE, Samarajiwa SA, de Weerd NA, Gould J, Argani P, Möller A, Smyth MJ, Anderson RL, Hertzog PJ, Parker BS. Bidwell BN, et al. Among authors: de weerd na. Nat Med. 2012 Aug;18(8):1224-31. doi: 10.1038/nm.2830. Epub 2012 Jul 22. Nat Med. 2012. PMID: 22820642

6

Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1.

de Weerd NA, Vivian JP, Nguyen TK, Mangan NE, Gould JA, Braniff SJ, Zaker-Tabrizi L, Fung KY, Forster SC, Beddoe T, Reid HH, Rossjohn J, Hertzog PJ. de Weerd NA, et al. Nat Immunol. 2013 Sep;14(9):901-7. doi: 10.1038/ni.2667. Epub 2013 Jul 21. Nat Immunol. 2013. PMID: 23872679

7

Purification and biological characterization of soluble, recombinant mouse IFNβ expressed in insect cells.

Stifter SA, Gould JA, Mangan NE, Reid HH, Rossjohn J, Hertzog PJ, de Weerd NA. Stifter SA, et al. Protein Expr Purif. 2014 Feb;94:7-14. doi: 10.1016/j.pep.2013.10.019. Epub 2013 Nov 6. Protein Expr Purif. 2014. PMID: 24211771

8

Interferon epsilon promotes HIV restriction at multiple steps of viral replication.

Garcia-Minambres A, Eid SG, Mangan NE, Pade C, Lim SS, Matthews AY, de Weerd NA, Hertzog PJ, Mak J. Garcia-Minambres A, et al. Immunol Cell Biol. 2017 May;95(5):478-483. doi: 10.1038/icb.2016.123. Epub 2017 Jan 3. Immunol Cell Biol. 2017. PMID: 28045025

9

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling.

de Weerd NA, Matthews AY, Pattie PR, Bourke NM, Lim SS, Vivian JP, Rossjohn J, Hertzog PJ. de Weerd NA, et al. J Biol Chem. 2017 May 5;292(18):7554-7565. doi: 10.1074/jbc.M116.773788. Epub 2017 Mar 13. J Biol Chem. 2017. PMID: 28289093 Free PMC article.

10

Defining the distinct, intrinsic properties of the novel type I interferon, IFNϵ.

Stifter SA, Matthews AY, Mangan NE, Fung KY, Drew A, Tate MD, Soares da Costa TP, Hampsey D, Mayall J, Hansbro PM, Garcia Minambres A, Eid SG, Mak J, Scoble J, Lovrecz G, deWeerd NA, Hertzog PJ. Stifter SA, et al. J Biol Chem. 2018 Mar 2;293(9):3168-3179. doi: 10.1074/jbc.M117.800755. Epub 2017 Nov 29. J Biol Chem. 2018. PMID: 29187603 Free PMC article.

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