Jia W - Search Results

1

In vitro and in vivo evaluation of amorphous solid dispersions generated by different bench-scale processes, using griseofulvin as a model compound.

Chiang PC, Cui Y, Ran Y, Lubach J, Chou KJ, Bao L, Jia W, La H, Hau J, Sambrone A, Qin A, Deng Y, Wong H. Chiang PC, et al. Among authors: jia w. AAPS J. 2013 Apr;15(2):608-17. doi: 10.1208/s12248-013-9469-3. Epub 2013 Mar 2. AAPS J. 2013. PMID: 23456436 Free PMC article.

2

Evaluation of dried blood spot sampling following cassette dosing in drug discovery.

Liang X, Yang L, Berezhkovskiy L, Liederer B, Nguyen T, Jia W, Schweiger M, Dean B, Deng Y. Liang X, et al. Among authors: jia w. Bioanalysis. 2011 Oct;3(20):2291-302. doi: 10.4155/bio.11.205. Bioanalysis. 2011. PMID: 22011177

3

GDC-0449-a potent inhibitor of the hedgehog pathway.

Robarge KD, Brunton SA, Castanedo GM, Cui Y, Dina MS, Goldsmith R, Gould SE, Guichert O, Gunzner JL, Halladay J, Jia W, Khojasteh C, Koehler MF, Kotkow K, La H, Lalonde RL, Lau K, Lee L, Marshall D, Marsters JC Jr, Murray LJ, Qian C, Rubin LL, Salphati L, Stanley MS, Stibbard JH, Sutherlin DP, Ubhayaker S, Wang S, Wong S, Xie M. Robarge KD, et al. Among authors: jia w. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5576-81. doi: 10.1016/j.bmcl.2009.08.049. Epub 2009 Aug 15. Bioorg Med Chem Lett. 2009. PMID: 19716296

4

Impact of Method of Preparation of Amorphous Solid Dispersions on Mechanical Properties: Comparison of Coprecipitation and Spray Drying.

Hou HH, Rajesh A, Pandya KM, Lubach JW, Muliadi A, Yost E, Jia W, Nagapudi K. Hou HH, et al. Among authors: jia w. J Pharm Sci. 2019 Feb;108(2):870-879. doi: 10.1016/j.xphs.2018.09.008. Epub 2018 Sep 19. J Pharm Sci. 2019. PMID: 30244013

5

Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma.

Wang X, Blackaby W, Allen V, Chan GKY, Chang JH, Chiang PC, Diène C, Drummond J, Do S, Fan E, Harstad EB, Hodges A, Hu H, Jia W, Kofie W, Kolesnikov A, Lyssikatos JP, Ly J, Matteucci M, Moffat JG, Munugalavadla V, Murray J, Nash D, Noland CL, Del Rosario G, Ross L, Rouse C, Sharpe A, Slaga D, Sun M, Tsui V, Wallweber H, Yu SF, Ebens AJ. Wang X, et al. Among authors: jia w. J Med Chem. 2019 Feb 28;62(4):2140-2153. doi: 10.1021/acs.jmedchem.8b01857. Epub 2019 Feb 20. J Med Chem. 2019. PMID: 30715878

6

Investigations into the mechanisms of pyridine ring cleavage in vismodegib.

Khojasteh SC, Yue Q, Ma S, Castanedo G, Chen JZ, Lyssikatos J, Mulder T, Takahashi R, Ly J, Messick K, Jia W, Liu L, Hop CE, Wong H. Khojasteh SC, et al. Among authors: jia w. Drug Metab Dispos. 2014 Mar;42(3):343-51. doi: 10.1124/dmd.113.055715. Epub 2014 Jan 3. Drug Metab Dispos. 2014. PMID: 24389420

7

Effect of Microenvironmental pH Modulation on the Dissolution Rate and Oral Absorption of the Salt of a Weak Acid - Case Study of GDC-0810.

Hou HH, Jia W, Liu L, Cheeti S, Li J, Nauka E, Nagapudi K. Hou HH, et al. Among authors: jia w. Pharm Res. 2018 Jan 29;35(2):37. doi: 10.1007/s11095-018-2347-z. Pharm Res. 2018. PMID: 29380076

8

Assessing the Interrelationship of Microstructure, Properties, Drug Release Performance, and Preparation Process for Amorphous Solid Dispersions Via Noninvasive Imaging Analytics and Material Characterization.

Jia W, Yawman PD, Pandya KM, Sluga K, Ng T, Kou D, Nagapudi K, Luner PE, Zhu A, Zhang S, Hou HH. Jia W, et al. Pharm Res. 2022 Dec;39(12):3137-3154. doi: 10.1007/s11095-022-03308-9. Epub 2022 Jun 3. Pharm Res. 2022. PMID: 35661085

9

The Significance of Fractional Exhaled Nitric Oxide, Fractional Nasal Exhaled Nitric Oxide and Lung Function Tests in Children with Moderate-to-Severe Allergic Rhinitis.

Li W, Jia W, Yi X, Li P, Song C. Li W, et al. Among authors: jia w. Am J Rhinol Allergy. 2025 Jan 15:19458924251313495. doi: 10.1177/19458924251313495. Online ahead of print. Am J Rhinol Allergy. 2025. PMID: 39814345

10

Discovery of robust and highly specific microbiome signatures of non-alcoholic fatty liver disease.

Nychas E, Marfil-Sánchez A, Chen X, Mirhakkak M, Li H, Jia W, Xu A, Nielsen HB, Nieuwdorp M, Loomba R, Ni Y, Panagiotou G. Nychas E, et al. Among authors: jia w. Microbiome. 2025 Jan 14;13(1):10. doi: 10.1186/s40168-024-01990-y. Microbiome. 2025. PMID: 39810263 Free PMC article.

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