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Multivalent Galalpha1,3Gal-substitution makes recombinant mucin-immunoglobulins efficient absorbers of anti-pig antibodies.
Liu J, Weintraub A, Holgersson J. Liu J, et al. Xenotransplantation. 2003 Mar;10(2):149-63. doi: 10.1034/j.1399-3089.2003.01144.x. Xenotransplantation. 2003. PMID: 12588648
A novel recombinant absorber of anti-pig antibodies was developed by fusing the cDNA encoding the extracellular part of a mucin-type protein, P-selectin glycoprotein ligand-1, with an antibody Fc fragment cDNA, which upon coexpression with the porcine alpha1,3 galactosyltransfera …
A novel recombinant absorber of anti-pig antibodies was developed by fusing the cDNA encoding the extracellular part of a mucin-type protein …
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