Segovia M - Search Results

1

Benznidazole treatment reduces the induction of indoleamine 2,3-dioxygenase (IDO) enzymatic activity in Chagas disease symptomatic patients.

Marañón C, Egui A, Fernández-Villegas A, Carrilero B, Thomas MC, Segovia M, López MC. Marañón C, et al. Among authors: segovia m. Parasite Immunol. 2013 May-Jun;35(5-6):180-7. doi: 10.1111/pim.12030. Parasite Immunol. 2013. PMID: 23473453

2

Short-term follow-up of chagasic patients after benzonidazole treatment using multiple serological markers.

Fernández-Villegas A, Pinazo MJ, Marañón C, Thomas MC, Posada E, Carrilero B, Segovia M, Gascon J, López MC. Fernández-Villegas A, et al. Among authors: segovia m. BMC Infect Dis. 2011 Jul 31;11:206. doi: 10.1186/1471-2334-11-206. BMC Infect Dis. 2011. PMID: 21801456 Free PMC article.

3

Characterization of an immunodominant antigenic epitope from Trypanosoma cruzi as a biomarker of chronic Chagas' disease pathology.

Thomas MC, Fernández-Villegas A, Carrilero B, Marañón C, Saura D, Noya O, Segovia M, Alarcón de Noya B, Alonso C, López MC. Thomas MC, et al. Among authors: segovia m. Clin Vaccine Immunol. 2012 Feb;19(2):167-73. doi: 10.1128/CVI.05566-11. Epub 2011 Dec 7. Clin Vaccine Immunol. 2012. PMID: 22155766 Free PMC article.

4

Trypanosoma cruzi paraflagellar rod proteins 2 and 3 contain immunodominant CD8(+) T-cell epitopes that are recognized by cytotoxic T cells from Chagas disease patients.

Egui A, Thomas MC, Morell M, Marañón C, Carrilero B, Segovia M, Puerta CJ, Pinazo MJ, Rosas F, Gascón J, López MC. Egui A, et al. Among authors: segovia m. Mol Immunol. 2012 Oct;52(3-4):289-98. doi: 10.1016/j.molimm.2012.05.021. Epub 2012 Jun 29. Mol Immunol. 2012. PMID: 22750229

5

The innate immune response status correlates with a divergent clinical course in congenital Chagas disease of twins born in a non-endemic country.

Fernández-Villegas A, Thomas MC, Carrilero B, Téllez C, Marañón C, Murcia L, Moralo S, Alonso C, Segovia M, López MC. Fernández-Villegas A, et al. Among authors: segovia m. Acta Trop. 2014 Dec;140:84-90. doi: 10.1016/j.actatropica.2014.08.006. Epub 2014 Aug 19. Acta Trop. 2014. PMID: 25149352

6

A 12-mer repetitive antigenic epitope from Trypanosoma cruzi is a potential marker of therapeutic efficacy in chronic Chagas' disease.

Fernandez-Villegas A, Thomas MC, Carrilero B, Lasso P, Egui A, Murcia L, Segovia M, Alonso C, López MC. Fernandez-Villegas A, et al. Among authors: segovia m. J Antimicrob Chemother. 2016 Jul;71(7):2005-9. doi: 10.1093/jac/dkw090. Epub 2016 Apr 12. J Antimicrob Chemother. 2016. PMID: 27073267

7

Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4+CD8+ T cells in chronic Chagas disease patients.

Pérez-Antón E, Egui A, Thomas MC, Puerta CJ, González JM, Cuéllar A, Segovia M, López MC. Pérez-Antón E, et al. Among authors: segovia m. PLoS Negl Trop Dis. 2018 May 11;12(5):e0006480. doi: 10.1371/journal.pntd.0006480. eCollection 2018 May. PLoS Negl Trop Dis. 2018. PMID: 29750791 Free PMC article.

8

A Parasite Biomarker Set for Evaluating Benznidazole Treatment Efficacy in Patients with Chronic Asymptomatic Trypanosoma cruzi Infection.

Egui A, Thomas MC, Fernández-Villegas A, Pérez-Antón E, Gómez I, Carrilero B, Del Pozo Á, Ceballos M, Andrés-León E, López-Ruz MÁ, Gainza E, Oquiñena E, Segovia M, López MC. Egui A, et al. Among authors: segovia m. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e02436-18. doi: 10.1128/AAC.02436-18. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31358581 Free PMC article.

9

Immunological exhaustion and functional profile of CD8⁺ T lymphocytes as cellular biomarkers of therapeutic efficacy in chronic Chagas disease patients.

Pérez-Antón E, Egui A, Thomas MC, Simón M, Segovia M, López MC. Pérez-Antón E, et al. Among authors: segovia m. Acta Trop. 2020 Feb;202:105242. doi: 10.1016/j.actatropica.2019.105242. Epub 2019 Oct 25. Acta Trop. 2020. PMID: 31669531 Free article.

10

Differential phenotypic and functional profile of epitope-specific cytotoxic CD8⁺ T cells in benznidazole-treated chronic asymptomatic Chagas disease patients.

Egui A, López MC, Gómez I, Simón M, Segovia M, Thomas MC. Egui A, et al. Among authors: segovia m. Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1;1866(3):165629. doi: 10.1016/j.bbadis.2019.165629. Epub 2019 Dec 6. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 31816438 Free article.

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