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Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs.
Yoshihara H, Fukushima T, Hakuno F, Saeki Y, Tanaka K, Ito A, Yoshida M, Iemura S, Natsume T, Asano T, Chida K, Girnita L, Takahashi S. Yoshihara H, et al. Among authors: chida k. Biochem Biophys Res Commun. 2012 Jun 22;423(1):122-7. doi: 10.1016/j.bbrc.2012.05.093. Epub 2012 May 23. Biochem Biophys Res Commun. 2012. PMID: 22634009
Phosphatidylinositol 3-kinase (PI3K) activity bound to insulin-like growth factor-I (IGF-I) receptor, which is continuously sustained by IGF-I stimulation, is required for IGF-I-induced cell proliferation.
Fukushima T, Nakamura Y, Yamanaka D, Shibano T, Chida K, Minami S, Asano T, Hakuno F, Takahashi S. Fukushima T, et al. Among authors: chida k. J Biol Chem. 2012 Aug 24;287(35):29713-21. doi: 10.1074/jbc.M112.393074. Epub 2012 Jul 5. J Biol Chem. 2012. PMID: 22767591 Free PMC article.
Growth hormone inhibition of glucose uptake in adipocytes occurs without affecting GLUT4 translocation through an insulin receptor substrate-2-phosphatidylinositol 3-kinase-dependent pathway.
Sasaki-Suzuki N, Arai K, Ogata T, Kasahara K, Sakoda H, Chida K, Asano T, Pessin JE, Hakuno F, Takahashi S. Sasaki-Suzuki N, et al. Among authors: chida k. J Biol Chem. 2009 Mar 6;284(10):6061-70. doi: 10.1074/jbc.M808282200. Epub 2009 Jan 2. J Biol Chem. 2009. PMID: 19122000 Free PMC article.
867 results